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Submit Review(S)-(+)-Ketamine hydrochloride
说明： NMDA receptor antagonist; enantiomer of ketamine hydrochloride (Cat. No. 3131); neuroprotective
化学名： (S)-(+)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
纯度： ≥99% (HPLC)
生物活性 for (S)-(+)-Ketamine hydrochloride
(S)-(+)-Ketamine hydrochloride is a NMDA receptor antagonist. Displays neuroprotective efficacy in vitro.
Racemate also available.
技术数据 for (S)-(+)-Ketamine hydrochloride
| 分子量 | 274.19 |
| 公式 | C13H16ClNO.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 33643-47-9 |
| PubChem ID | 44632368 |
| InChI Key | VCMGMSHEPQENPE-ZOWNYOTGSA-N |
| Smiles | O=C1[C@](C2=CC=CC=C2Cl)(NC)CCCC1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for (S)-(+)-Ketamine hydrochloride
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 27.42 | 100 | |
| DMSO | 27.42 | 100 |
制备储备液 for (S)-(+)-Ketamine hydrochloride
以下数据基于产品分子量 274.19。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.65 mL | 18.24 mL | 36.47 mL |
| 5 mM | 0.73 mL | 3.65 mL | 7.29 mL |
| 10 mM | 0.36 mL | 1.82 mL | 3.65 mL |
| 50 mM | 0.07 mL | 0.36 mL | 0.73 mL |
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产品说明书 for (S)-(+)-Ketamine hydrochloride
参考文献 for (S)-(+)-Ketamine hydrochloride
参考文献是支持产品生物活性的出版物。
Ryder et al (1978) Comparative pharmacology of the optical isomers of KA in mice. Eur.J.Pharmacol. 49 15 PMID: 658124
Proescholdt et al (2001) Neuroprotection of S(+) KA isomer in global forebrain ischemia. Brain Res. 904 245 PMID: 11406122
Benrath et al (2005) Low dose of S(+)-KA prevents long-term potentiation in pain pathways under strong opioid analgesia in the rat spinal cord in vivo. Br.J.Anaesth. 95 518 PMID: 16113037
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关键词: (S)-(+)-Ketamine hydrochloride, (S)-(+)-Ketamine hydrochloride supplier, nmda, nmdar, antagonists, NMDA, Receptors, Ketamine, and, Metabolites, 4379, Tocris Bioscience
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