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Submit ReviewSGC AAK1 1N is a negative control for SGC AAK1 1 (Cat. No. 6528).
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the SGC-AAK1-1 probe summary on the SGC website.
分子量 | 398.48 |
公式 | C20H22N4O3S |
储存 | Store at -20°C |
纯度 | ≥97% (HPLC) |
CAS Number | 2242913-80-8 |
PubChem ID | 146121078 |
InChI Key | RAIAORGFMNXPOV-UHFFFAOYSA-N |
Smiles | O=C(C(C)C)NC1=NNC2=C1C=CC(C3=CC=CC(NS(=O)(C4CC4)=O)=C3)=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 39.85 | 100 | |
ethanol | 3.98 | 10 |
以下数据基于产品分子量 398.48。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 2.51 mL | 12.55 mL | 25.1 mL |
5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
10 mM | 0.25 mL | 1.25 mL | 2.51 mL |
50 mM | 0.05 mL | 0.25 mL | 0.5 mL |
参考文献是支持产品生物活性的出版物。
Agajanian (2019) WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop. Cell Rep. 26 79 PMID: 30605688
If you know of a relevant reference for SGC AAK1 1N, please let us know.
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