主页 / 药理学 / Enzymes / Kinases / Other Kinases / Other Kinase Inhibitors / STK16-IN-1

STK16-IN-1

Cat. No. 6036 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6036 has been discontinued.

View all Other Kinases products.
说明： Serine/threonine protein kinase 16 (STK16) inhibitor; also inhibits PI 3Kδ, PI 3Kγ and mTOR kinases
化学名： 1-(4-Fluoro-3-methylphenyl)-1,7-dihydro-2H-pyrrolo[2,3-h]-1,6-naphthyridin-2-one
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for STK16-IN-1

STK16-IN-1 is a serine/threonine protein kinase 16 (STK16) inhibitor (IC50 = 295 nM). Reduces cell number and increases accumulation of binucleated MCF-1 cells. Enhances cell apoptosis in combination with chemotherapeutics. Also inhibits PI 3-Kδ and PI-3-Kγ kinases (IC50 values are 856 and 867 nM, respectively) and mTOR kinase (IC50= 5.56 μM).

许可信息

Sold under license from Whitehead Institute for Biomedical Research.

技术数据 for STK16-IN-1

分子量 293.3
公式 C17H12FN3O
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 1223001-53-3
PubChem ID 58525066
InChI Key WQNRDXHKVSKUPI-UHFFFAOYSA-N
Smiles O=C(N1C2=CC(C)=C(F)C=C2)C=CC3=C1C(C=CN4)=C4N=C3

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for STK16-IN-1

参考文献是支持产品生物活性的出版物。

Liu et al (2016) Discovery of a highly selective STK16 kinase inhibitor ACS.Chem.Biol. 11 1537 PMID: 27082499

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Other Kinase Inhibitors

关键词: STK16-IN-1, STK16-IN-1 supplier, Serine/Threonine, kinase, Ser/Thr, STK16, STK16-IN-1, inhibitors, inhibits, binucleated, cells, apoptosis, chemotherapy, chemotherapeutics, PI, 3K, mTOR, Other, Kinases, 3-Kinase, 6036, Tocris Bioscience

篇 STK16-IN-1 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 STK16-IN-1 的引用文献。

STK16-IN-1 的评论

目前没有该产品的评论。 Be the first to review STK16-IN-1 and earn rewards!

Have you used STK16-IN-1?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review