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Submit ReviewTBTA is a click chemistry auxiliary reagent. It is a stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reactions.
分子量 | 530.6 |
公式 | C30H30N10 |
储存 | Store at -20°C |
纯度 | ≥97% (HPLC) |
CAS Number | 510758-28-8 |
PubChem ID | 11203363 |
InChI Key | WKGZJBVXZWCZQC-UHFFFAOYSA-N |
Smiles | N1(CC2=CC=CC=C2)N=NC(CN(CC3=CN(CC4=CC=CC=C4)N=N3)CC5=CN(CC6=CC=CC=C6)N=N5)=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 53.06 | 100 |
以下数据基于产品分子量 530.6。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.88 mL | 9.42 mL | 18.85 mL |
5 mM | 0.38 mL | 1.88 mL | 3.77 mL |
10 mM | 0.19 mL | 0.94 mL | 1.88 mL |
50 mM | 0.04 mL | 0.19 mL | 0.38 mL |
参考文献是支持产品生物活性的出版物。
Pang et al (2022) In situ identification of cellular drug targets in mammalian tissue. Cell 185 1793 PMID: 35483372
Fantoni et al (2021) A hitchhiker's guide to click-chemistry with nucleic acids. Chem.Rev. 121 7122 PMID: 33443411
Kour et al (2021) Stapling proteins in the RELA complex inhibits TNFα-induced nuclear translocation of RELA. RSC Chem.Biol. 3 32 PMID: 35128406
If you know of a relevant reference for TBTA, please let us know.
关键词: TBTA, TBTA supplier, Click, Chemistry, azide, alkyne, copper, Cu, catalyzed, stabilizing, ligand, cu, cycloaddition, Biochemicals, and, Molecular, Biology, 7862, Tocris Bioscience
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