JAK Inhibitors

Cat. No. Product Name / Activity
0414 AG 490
JAK2, JAK3 inhibitor. Also EGFR-kinase inhibitor
5617 AZD 1480
Potent and selective JAK2 inhibitor; antiangiogenic
7222 Baricitinib
Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
4500 Cercosporamide
Potent Mnk2 inhibitor; also inhibits JAK3
4556 CP 690550 citrate
Potent JAK inhibitor
1571 Cucurbitacin I
Selective inhibitor of STAT3/JAK2 signaling
3395 Lestaurtinib
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
6506 PF 06551600 malonate
Potent and selective JAK3 inhibitor
6577 Pyridone 6
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
7064 Ruxolitinib
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
7048 Ruxolitinib phosphate
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
3035 SD 1008
JAK2/STAT3 signaling pathway inhibitor
6125 TC JL 37
Potent TYK2 inhibitor
4221 TCS 21311
Potent JAK3 inhibitor. Also inhibits GSK-3β and PKC
7783 Upadacitinib
JAK1-selective inhibitor
1367 ZM 39923 hydrochloride
Potent, selective JAK3 inhibitor