Home / Product Type / Reagents / Unnatural Amino Acids / Non Canonical Amino Acids / 3-Aminotyrosine

3-Aminotyrosine

Cat. No. 7370 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Unnatural amino acid for inducing red shift in fluorescent proteins and fluorescent protein-based biosensors
Chemical Name: 3-Amino-L-tyrosine dihydrochloride
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for 3-Aminotyrosine

3-Aminotyrosine is an unnatural amino acid that induces red shift when incorporated into fluorescent proteins and fluorescent protein-based biosensors. Causes spontaneous and efficient red shift of GFP in HEK293T cells, shifting excitation and emission maxima by 56 and 95 nm respectively. Induces red shift in a range of fluorescent proteins containing tyrosine-derived chromophores, including teal fluorescent mTFP1, yellow fluorescent Citrine, and circularly permuted YFP and GFP. Also induces red-shift in fluorescent protein-based biosensors, including iGluSnFR (a glutamate sensor), iGABASnFR (a GABA sensor), dLight1.2 (a dopamine sensor) and iATPSnFR1.1 (an ATP sensor).

Technical Data for 3-Aminotyrosine

M. Wt 269.12
Formula C9H12N2O3.2HCl
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 23279-22-3
PubChem ID 46735196
InChI Key PIFWBMTWCTUOOQ-KLXURFKVSA-N
Smiles N[C@H](C(O)=O)CC1=CC(N)=C(C=C1)O.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for 3-Aminotyrosine

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 26.91 100
DMSO 26.91 100

Preparing Stock Solutions for 3-Aminotyrosine

The following data is based on the product molecular weight 269.12. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.72 mL 18.58 mL 37.16 mL
5 mM 0.74 mL 3.72 mL 7.43 mL
10 mM 0.37 mL 1.86 mL 3.72 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for 3-Aminotyrosine

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for 3-Aminotyrosine

References are publications that support the biological activity of the product.

Zhang & Ai (2020) A general strategy to red-shift green fluorescent protein-based biosensors. Nat.Chem.Biol. 16 1434 PMID: 32929278

If you know of a relevant reference for 3-Aminotyrosine, please let us know.

View Related Products by Target

Keywords: 3-Aminotyrosine, 3-Aminotyrosine supplier, red, shift, fluorescent, protein, based, biosensors, GFP, YFP, TFP, noncanonical, unnatural, amino, acids, UAA, Unnatural, Amino, Acids, 7370, Tocris Bioscience

Citations for 3-Aminotyrosine

Citations are publications that use Tocris products.

Currently there are no citations for 3-Aminotyrosine. Do you know of a great paper that uses 3-Aminotyrosine from Tocris? Please let us know.

Reviews for 3-Aminotyrosine

There are currently no reviews for this product. Be the first to review 3-Aminotyrosine and earn rewards!

Have you used 3-Aminotyrosine?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals