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α-Cyclodextrin

Cat. No. 3180 Submit a Review Datasheet / COA / SDS
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Description: Cyclic complexing agent
Purity: ≥98% (HPLC)
Datasheet
Citations
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for α-Cyclodextrin

α-Cyclodextrin (α-CD) is a cylindrical oligosaccharide presenting a hydrophilic surface and a lipophilic cavity. α-Cyclodextrin can form inclusion complexes with a diverse range of hydrophobic compounds. These complexes increase the aqueous solubility, dissolution rate, and bioavailability of the guest compounds.

Technical Data for α-Cyclodextrin

M. Wt 972.85
Formula C36H60O30
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 10016-20-3
PubChem ID 444913
InChI Key HFHDHCJBZVLPGP-RWMJIURBSA-N
Smiles C(O)[C@@H]1[C@@]2([C@H](O)[C@@H](O)[C@](O1)(O[C@@]3([C@@H](CO)O[C@@]([C@H](O)[C@H]3O)(O[C@@]4([C@@H](CO)O[C@@]([C@H](O)[C@H]4O)(O[C@]5([C@H](O)[C@@H](O)[C@@](O[C@]6([C@H](O)[C@@H](O)[C@@](O[C@]7([C@H](O)[C@@H](O)[C@@](O2)(O[C@@H]7CO)[H])[H])(O[C@@H]6CO)[H])[H])(O[C@@H]5CO)[H])[H])[H])[H])[H])[H])[H])[H]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for α-Cyclodextrin

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 97.28 100
water 97.28 100

Preparing Stock Solutions for α-Cyclodextrin

The following data is based on the product molecular weight 972.85. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.03 mL 5.14 mL 10.28 mL
5 mM 0.21 mL 1.03 mL 2.06 mL
10 mM 0.1 mL 0.51 mL 1.03 mL
50 mM 0.02 mL 0.1 mL 0.21 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets for α-Cyclodextrin

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for α-Cyclodextrin

References are publications that support the biological activity of the product.

Rodriguez-Aller et al (2015) New prostaglandin analog formulation for glaucoma treatment containing cyclodextrins for improved stability, solubility and ocular tolerance. Eur.J.Pharm.Biopharm. 95 203 PMID: 25960331

If you know of a relevant reference for α-Cyclodextrin, please let us know.

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Citations for α-Cyclodextrin

Citations are publications that use Tocris products.

Currently there are no citations for α-Cyclodextrin. Do you know of a great paper that uses α-Cyclodextrin from Tocris? Please let us know.

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