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β-Cyclodextrin

Cat. No. 3181 Submit a Review Datasheet / COA / SDS
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Description: Cyclic complexing agent
Purity: ≥98% (HPLC)
Datasheet
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for β-Cyclodextrin

β-Cyclodextrin (β-CD) is a cyclic oligosaccharide comprising seven glucose subunits linked by α-1,4-glycosidic bonds, forming a cage-like supramolecular structure with a hydrophobic interior and a hydrophilic exterior. β-Cyclodextrins can form inclusion complexes with a diverse range of hydrophobic compounds. These complexes increase the aqueous solubility, dissolution rate, and bioavailability of the guest compounds.

Technical Data for β-Cyclodextrin

M. Wt 1134.99
Formula C42H70O35
Storage Store at RT
Purity ≥98% (HPLC)
CAS Number 7585-39-9
InChI Key WHGYBXFWUBPSRW-FOUAGVGXSA-N
Smiles O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@H](O)[C@@H](O)[C@H](O3)[C@@H](CO)O2)[C@@H](CO)O[C@@H]1O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)[C@@H](O[C@H]8[C@H](O)[C@@H](O)[C@@H]3O[C@@H]8CO)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for β-Cyclodextrin

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 113.5 100
water 11.35 10

Preparing Stock Solutions for β-Cyclodextrin

The following data is based on the product molecular weight 1134.99. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 0.88 mL 4.41 mL 8.81 mL
5 mM 0.18 mL 0.88 mL 1.76 mL
10 mM 0.09 mL 0.44 mL 0.88 mL
50 mM 0.02 mL 0.09 mL 0.18 mL

Molarity Calculator

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Product Datasheets for β-Cyclodextrin

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for β-Cyclodextrin

References are publications that support the biological activity of the product.

Armstrong et al (1986) Separation of drug stereoisomers by the formation of beta-cyclodextrin inclusion complexes. Science 232 1132 PMID: 3704640

If you know of a relevant reference for β-Cyclodextrin, please let us know.

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Citations for β-Cyclodextrin

Citations are publications that use Tocris products.

Currently there are no citations for β-Cyclodextrin. Do you know of a great paper that uses β-Cyclodextrin from Tocris? Please let us know.

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