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Submit ReviewBiotin-11-dUTP
Description: Biotin-labeled dUTP
Chemical Name: 2'-Deoxy-5-[(1E)-3-[[6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-1-oxohexyl]amino]-1-propen-1-yl]uridine 5'-(tetra(triethylammonium) triphosphate)
Purity: ≥95% (HPLC)
Biological Activity for Biotin-11-dUTP
Biotin-11-dUTP is a biotin-labeled dUTP. Commonly used in PCR, nick translation, and reverse transcription. Also frequently used in apoptosis assays. Biotin-labeled DNA may be detected with streptavidin-HRP conjugates.
Technical Data for Biotin-11-dUTP
| M. Wt | 1267.43 |
| Formula | C28H45N6O17P3S.4(C2H5)3N |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| PubChem ID | 101939310 |
| InChI Key | AZRNEVJSOSKAOC-PEFKSLAVSA-N |
| Smiles | [H][C@]12CS[C@H]([C@]1(NC(N2)=O)[H])CCCCC(NCCCCCC(NC/C=C/C3=CN(C(NC3=O)=O)[C@H]4C[C@@H]([C@H](O4)COP([O-])(OP([O-])(OP([O-])([O-])=O)=O)=O)O)=O)=O.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC.CC[N+]([H])(CC)CC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for Biotin-11-dUTP
| Solubility | Soluble to 1 mM in 10mM Tris-HCl buffer (supplied pre-dissolved - 1mM) |
Product Datasheets for Biotin-11-dUTP
References for Biotin-11-dUTP
References are publications that support the biological activity of the product.
Jun-Hyuk Choi et al (2015) An integrated approach for analysis of the DNA damage response in mammalian cells J.Biol.Chem. 290 2881 PMID: 26438822
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Citations for Biotin-11-dUTP
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