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CSN5i-3-NEG

Cat. No. 7532 Submit a Review Datasheet / COA / SDS
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Description: Negative control for CSN5i-3 (Cat. No. 7089)
Chemical Name: 3-(Difluoromethyl)-N-(6-((5R,6R)-6-hydroxy-6,7,8,9-tetrahydro-5H-imidazo[1,5-a]azepin-5-yl)-[1,10-biphenyl]-3-yl)-1-isopropyl-1H-pyrazole-5-carboxamide
Purity: ≥98% (HPLC)
Datasheet
Citations
Reviews
Literature (3)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for CSN5i-3-NEG

CSN5i-3-NEG is the negative control for CSN5i-3 (Cat. No.7089).

Technical Data for CSN5i-3-NEG

M. Wt 505.57
Formula C28H29F2N5O2
Storage Store at -20°C
Purity ≥98% (HPLC)
CAS Number 2863607-74-1
PubChem ID 145712311
InChI Key ANNKHJQLDMGQFM-CLJLJLNGSA-N
Smiles CC(N1N=C(C(F)F)C=C1C(NC2=CC(C3=CC=CC=C3)=C([C@@H]4[C@@H](CCCC5=CN=CN45)O)C=C2)=O)C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for CSN5i-3-NEG

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50.56 100

Preparing Stock Solutions for CSN5i-3-NEG

The following data is based on the product molecular weight 505.57. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.98 mL 9.89 mL 19.78 mL
5 mM 0.4 mL 1.98 mL 3.96 mL
10 mM 0.2 mL 0.99 mL 1.98 mL
50 mM 0.04 mL 0.2 mL 0.4 mL

Molarity Calculator

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Reconstitution Calculator

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References for CSN5i-3-NEG

References are publications that support the biological activity of the product.

If you know of a relevant reference for CSN5i-3-NEG, please let us know.

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Keywords: CSN5i-3-NEG, CSN5i-3-NEG supplier, negative, controls, CSN5, COP9, signalosome, antitumour, antitumor, Constitutive, photomorphogenesis, 9, NEDD8, neddylation, cullin-ring, CRL, Ubiquitin, E3, Ligases, 7532, Tocris Bioscience

Citations for CSN5i-3-NEG

Citations are publications that use Tocris products.

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Literature in this Area

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TPD and Induced Proximity Research Product Guide

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