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Submit ReviewCyanine 5.5, SE
Description: Far red fluorescent dye for the labeling of amines; supplied as NHS ester
Alternative Names: Cy5.5,Sulpho-Cyanine 5.5
Chemical Name: Tris(triethylammonium) 3-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-2-((1E,3E,5Z)-5-(3-ethyl-1,1-dimethyl-6,8-disulfonato-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-6,8-disulfonate
Purity: ≥90% (HPLC)
Biological Activity for Cyanine 5.5, SE
Cyanine 5.5, SE is a far red fluorescent dye for the labeling of amines. Cyanine 5.5, SE is ideal for labeling antibodies, peptides, glycoproteins, and amine-rich proteins. Cyanine 5.5, SE is also suitable for in vivo imaging. Excitation maximum ~675 nm; emission maximum ~694 nm.
Optical Data for Cyanine 5.5, SE
| Emission Color | Far Red |
|---|---|
| λabs | 675 nm |
| λem | 694 nm |
| Extinction Coefficient (ε) | 190000 M-1cm-1 |
| Quantum Yield (φ) | 0.28 |
| Reactive Group | NHS ester |
| Application | labeling antibodies, peptides, glycoproteins, and amine-rich proteins - suitable for in vivo imaging |
| Alternative For | Alexa Fluor® 680, and DyLight 680 |
Alexa Fluor® is a registered trademark of Molecular Probes, Inc, a Thermo Fisher Scientific Company.
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
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Technical Data for Cyanine 5.5, SE
| M. Wt | 1317.7 |
| Formula | C45H44N3O16S4.3C6H15NH |
| Storage | Store at -20°C |
| Purity | ≥90% (HPLC) |
| InChI Key | GECMOSJJYVCJFX-UHFFFAOYSA-N |
| Smiles | CCN1C2=C(C(C)(/C1=C/C=C/C=C/C3=[N+](C4=C(C3(C)C)C5=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C5C=C4)CCCCCC(ON6C(CCC6=O)=O)=O)C)C7=CC(S([O-])(=O)=O)=CC(S([O-])(=O)=O)=C7C=C2.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC.CC[N+](CC)([H])CC |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for Cyanine 5.5, SE
References for Cyanine 5.5, SE
References are publications that support the biological activity of the product.
Ma et al (2012) Ultrasmall sub-10 nm near-infrared fluorescent mesoporous silica nanoparticles. J.Am.Chem.Soc. 134 13180 PMID: 22830608
Kim et al (2006) Cell-permeable and biocompatible polymeric nanoparticles for apoptosis imaging. J.Am.Chem.Soc. 128 3490 PMID: 16536501
Weissleder et al (1999) In vivo imaging of tumors with protease-activated near-infrared fluorescent probes. Nat.Biotechnol 17 375 PMID: 10207887
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Citations for Cyanine 5.5, SE
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Fluorescent Dyes and Probes Research Product GuideUpdated
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