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Description: Amine reactive and azide reactive building block
Chemical Name: 2,5-Dioxo-1-pyrrolidinyl-11,12-didehydro-γ-oxodibenz[b,f]azocine-5(6H)-butanoate
Purity: ≥95% (HPLC)
Biological Activity for DBCO-NHS
DBCO-NHS is an amine reactive and azide reactive building block. It can be used for copper-free click cycloaddition reactions.
Usage Guidelines for DBCO-NHS
This product is provided for use in onward chemistry. Suitable solvents can be used.
Technical Data for DBCO-NHS
| M. Wt | 402.4 |
| Formula | C23H18N2O5 |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 1353016-71-3 |
| PubChem ID | 77078178 |
| InChI Key | XCEBOJWFQSQZKR-UHFFFAOYSA-N |
| Smiles | O=C(ON1C(=O)CCC1=O)CCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Product Datasheets for DBCO-NHS
References for DBCO-NHS
References are publications that support the biological activity of the product.
Liu et al (2012) Strain-promoted "click" modification of a mesoporous metal-organic framework. J.Am.Chem.Soc. 134 18886 PMID: 23113571
Ge et al (2022) Chemoselective bioconjugation of amyloidogenic protein antigens to PEGylated microspheres enables detection of α-Synuclein autoantibodies in human plasma. Bioconjug.Chem. 33 301 PMID: 35020392
If you know of a relevant reference for DBCO-NHS, please let us know.
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Citations for DBCO-NHS
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