Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewHaXS8 is a chemical dimerizer that promotes covalent and irreversible HaloTag® and SNAP-tag® substrate dimerization. Cell permeable.
HaloTag is a trademark of Promega Corporation, and SNAP-tag is a trademark of New England BioLabs, Inc.
M. Wt | 787.2 |
Formula | C35H43ClF4N6O8 |
Storage | Store at -20°C |
Purity | ≥90% (HPLC) |
CAS Number | 2080306-25-6 |
PubChem ID | 124201846 |
InChI Key | OHHUCZCSUXJJFO-UHFFFAOYSA-N |
Smiles | NC1=NC2=C(N=CN2)C(OCC3=CC=C(CNC(COC4=C(F)C(F)=C(OCCOCCOCCOCCOCCCCCCCl)C(F)=C4F)=O)C=C3)=N1 |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solvent | Max Conc. mg/mL | Max Conc. mM | |
---|---|---|---|
Solubility | |||
DMSO | 78.72 | 100 |
The following data is based on the product molecular weight 787.2. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.27 mL | 6.35 mL | 12.7 mL |
5 mM | 0.25 mL | 1.27 mL | 2.54 mL |
10 mM | 0.13 mL | 0.64 mL | 1.27 mL |
50 mM | 0.03 mL | 0.13 mL | 0.25 mL |
References are publications that support the biological activity of the product.
Erhart et al (2013) Chemical development of intracellular protein heterodimerizers. Chem.Biol. 20 549 PMID: 23601644
Zimmermann et al (2014) Cell-permeant and photocleavable chemical inducer of dimerization. Angew Chem.Int.Ed.Engl. 53 4717 PMID: 24677313
If you know of a relevant reference for HaXS8, please let us know.
Keywords: HaXS8, HaXS8 supplier, promotes, covalent, irreversible, HaloTag, SNAP-tag, dimerization, dimerizer, cell, permeable, Biochemicals, and, Molecular, Biology, Protein, Dimerizers, 4991, Tocris Bioscience
Citations are publications that use Tocris products.
Currently there are no citations for HaXS8. Do you know of a great paper that uses HaXS8 from Tocris? Please let us know.
There are currently no reviews for this product. Be the first to review HaXS8 and earn rewards!
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image