Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewICG-d7
Description: Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging.
Chemical Name: Sodium 4-(2-((1E,3E,5E,7Z)-7-(1,1-Dimethyl-3-(4-sulfonatobutyl)-1,3-dihydro-2H-benzo[e]indol-2-ylidene)hepta-1,3,5-trien-1-yl-1,2,3,4,5,6,7-d7)-1,1-dimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate
Purity: ≥95% (HPLC)
Biological Activity for ICG-d7
Key information: ICG-d7 is a partially deuterated form of near-infrared fluorescent dye Indocyanine Green (ICG; Cat. No. 7510).
Application: Fluorescence microscopy, in vivo imaging.
Properties and Photophysical Data: ICG-d7 operates in the 700 - 900 nm wavelength range; also exhibits fluorescence emission in the shortwave infrared window (SWIR; 1,000 - 2,000 nm) which enables in vivo imaging. ICG-d7 shows improved stability in aqueous solutions over ICG with the same fluorescence brightness, and similar absorption and emission maxima in both DMSO and FBS. Excitation and emission maxima (λ) are 794 nm and 818 nm, respectively; quantum yield = 0.21; extinction coefficient = 228,000 M-1cm-1.
Licensing Information
Sold under license from the University of Notre Dame
Optical Data for ICG-d7
| Emission Color | Near-IR |
|---|---|
| λabs | 794 nm |
| λem | 818 nm |
| Extinction Coefficient (ε) | 228000 M-1cm-1 |
| Quantum Yield (φ) | 0.21 |
| Application | Fluorescence Microscopy, In Vivo Imaging |
| Alternative For | Indocyanine green |
Plan Your Experiments
Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.
Spectral Viewer
Technical Data for ICG-d7
| M. Wt | 782.01 |
| Formula | C43H40D7N2O6S2Na |
| Storage | Store at -20°C |
| Purity | ≥95% (HPLC) |
| CAS Number | 2861905-57-7 |
| InChI Key | MOFVSTNWEDAEEK-ZMRQXZMGSA-M |
| Smiles | CC1(C)/C(N(CCCCS(=O)(O[Na])=O)C2=C1C3=CC=CC=C3C=C2)=C(/C([2H])=C(/C([2H])=C(/C([2H])=C(C4=[N+](CCCCS([O-])(=O)=O)C5=C(C6=CC=CC=C6C=C5)C4(C)C)\[2H])[2H])[2H])[2H] |
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Solubility Data for ICG-d7
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 7.82 | 10 | |
| DMSO | 7.82 | 10 |
Preparing Stock Solutions for ICG-d7
The following data is based on the product molecular weight 782.01. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.79 mL | 63.94 mL | 127.88 mL |
| 0.5 mM | 2.56 mL | 12.79 mL | 25.58 mL |
| 1 mM | 1.28 mL | 6.39 mL | 12.79 mL |
| 5 mM | 0.26 mL | 1.28 mL | 2.56 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
Product Datasheets for ICG-d7
References for ICG-d7
References are publications that support the biological activity of the product.
Li and Smith (2021) Deuterated indocyanine green (ICG) with extended aqueous storage shelf-life: chemical and clinical implications. Chemistry 27 14535 PMID: 34403531
If you know of a relevant reference for ICG-d7, please let us know.
View Related Products by Target
Keywords: ICG-d7, ICG-d7 supplier, ICGd7, indocyanine, cyanine, green, deuterated, deuterium, NIR, near, infrared, fluorescent, fluorescence, stable, stability, short, wave, infra, red, labeling, Near, Infrared, (NIR), Fluorescent, Dyes, Cyanine, (Cy, Dyes), Stable, Isotopically, Labeled, Compounds, 7749, Tocris Bioscience
Citations for ICG-d7
Citations are publications that use Tocris products.
Currently there are no citations for ICG-d7. Do you know of a great paper that uses ICG-d7 from Tocris? Please let us know.
Reviews for ICG-d7
There are currently no reviews for this product. Be the first to review ICG-d7 and earn rewards!
Have you used ICG-d7?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Literature in this Area
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*Please note that Tocris will only send literature to established scientific business / institute addresses.
Fluorescent Dyes and Probes Research Product Guide
This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:
- Fluorescent Dyes, including dyes for flow cytometry
- Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
- Tissue Clearing Kits and Reagents
- Aptamer-based RNA Imaging Reagents
- Fluorescent Probes for Imaging Bacteria
- TSA VividTM Fluorophore Kits
- TSA Reagents for Enhancing IHC, ICC & FISH Signals