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THPTA

Cat. No. 7863 Submit a Review Datasheet / COA / SDS
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Description: Click chemistry auxiliary reagent; accelerating ligand for copper-catalyzed azide-alkyne cycloaddition reaction
Chemical Name: Tris[(1-(3-hydroxypropyl)-1H-1,2,3-triazol-4-yl]methyl)amine
Purity: ≥95% (HPLC)
Datasheet
Citations
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Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for THPTA

THPTA is a click chemistry auxiliary reagent. It is a stabilizing ligand for copper-catalyzed azide-alkyne cycloaddition reactions.

Technical Data for THPTA

M. Wt 434.51
Formula C18H30N10O3
Storage Store at -20°C
Purity ≥95% (HPLC)
CAS Number 760952-88-3
PubChem ID 85325313
InChI Key VAKXPQHQQNOUEZ-UHFFFAOYSA-N
Smiles OCCCN1N=NC(CN(CC2=CN(CCCO)N=N2)CC3=CN(CCCO)N=N3)=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for THPTA

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 43.45 100
DMSO 43.45 100

Preparing Stock Solutions for THPTA

The following data is based on the product molecular weight 434.51. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.3 mL 11.51 mL 23.01 mL
5 mM 0.46 mL 2.3 mL 4.6 mL
10 mM 0.23 mL 1.15 mL 2.3 mL
50 mM 0.05 mL 0.23 mL 0.46 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

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Dilution Calculator

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Product Datasheets for THPTA

Certificate of Analysis / Product Datasheet
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Safety Datasheet

References for THPTA

References are publications that support the biological activity of the product.

Zhu et al (2020) Biomimetic α-selective ribosylation enables two-step modular synthesis of biologically important ADP-ribosylated peptides. Nat.Commun. 11 5600 PMID: 33154359

Fantoni et al (2021) A Hitchhiker's guide to click-chemistry with nucleic acids. Chem.Rev. 121 7122 PMID: 33443411

If you know of a relevant reference for THPTA, please let us know.

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Keywords: THPTA, THPTA supplier, Click, Chemistry, azide, alkyne, copper, Cu, catalyzed, stabilizing, ligand, cu, cycloaddition, Biochemicals, and, Molecular, Biology, 7863, Tocris Bioscience

Citations for THPTA

Citations are publications that use Tocris products.

Currently there are no citations for THPTA. Do you know of a great paper that uses THPTA from Tocris? Please let us know.

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