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Submit ReviewDC-Cholesterol hydrochloride is a cationic cholesterol derivative for use as a liposomal transfection reagent. Combines with the 'helper lipid' DOPE (Cat. No. 7175) after sonication or microfluidization to form unilamellar liposomes. Can be used in vitro and in vivo for transfer of nucleic acids, protein complexes, or other small molecule complexes into tissues, tumors and cells.
分子量 | 537.27 |
公式 | C32H56N2O2.HCl |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 166023-21-8 |
PubChem ID | 16219102 |
InChI Key | ISXSJGHXHUZXNF-LXZPIJOJSA-N |
Smiles | [H][C@]1([C@@H](CCCC(C)C)C)CC[C@]2([C@@]3(CC=C4C[C@@H](OC(NCCN(C)C)=O)CC[C@@]4([C@]3(CC[C@]12C)[H])C)[H])[H].Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
---|---|---|---|
溶解性 | |||
DMSO | 2.69 | 5 超声处理 | |
ethanol | 10.75 | 20 |
以下数据基于产品分子量 537.27。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.2 mM | 9.31 mL | 46.53 mL | 93.06 mL |
1 mM | 1.86 mL | 9.31 mL | 18.61 mL |
2 mM | 0.93 mL | 4.65 mL | 9.31 mL |
10 mM | 0.19 mL | 0.93 mL | 1.86 mL |
参考文献是支持产品生物活性的出版物。
Li et al (1996) DC-Chol lipid system in gene transfer. J.Control.Release 39 373
If you know of a relevant reference for DC-Cholesterol hydrochloride, please let us know.
关键词: DC-Cholesterol hydrochloride, DC-Cholesterol hydrochloride supplier, DCcholesterol, cholesterol, liposome, lipofection, lipid, transfection, nucleic, acid, transfer, Biochemicals, and, Molecular, Biology, Lipid, Nanoparticles, 7176, Tocris Bioscience
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