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DOTAP

Cat. No. 7179 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Cationic agent for liposome and LNP formation
别名： 1,2-dioleoyl-3-trimethylammoniumpropane
化学名： N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium chloride
纯度： ≥95% (HPLC)
说明书
引用文献
评论
实验方案 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for DOTAP

DOTAP is a cationic agent used in liposome formation. Facilitates the transfection of DNA, RNA, and other molecules with negative charges into eukaryotic cells. Can be used to generate selective organ-targeting (SORT) lipid nanoparticles.

For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.

技术数据 for DOTAP

分子量 698.54
公式 C42H80ClNO4
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 132172-61-3
InChI Key KSXTUUUQYQYKCR-LQDDAWAPNA-M
Smiles C(OC(CCCCCCC/C=C\CCCCCCCC)=O)(COC(CCCCCCC/C=C\CCCCCCCC)=O)C[N+](C)(C)C.[Cl-]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DOTAP

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
ethanol 69.85 100
chloroform 69.85 100

制备储备液 for DOTAP

以下数据基于产品分子量 698.54。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.43 mL 7.16 mL 14.32 mL
5 mM 0.29 mL 1.43 mL 2.86 mL
10 mM 0.14 mL 0.72 mL 1.43 mL
50 mM 0.03 mL 0.14 mL 0.29 mL

Molarity Calculator

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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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参考文献 for DOTAP

参考文献是支持产品生物活性的出版物。

Wang et al (2023) Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery. Nat.Protoc. 18 265 PMID: 36316378

If you know of a relevant reference for DOTAP, please let us know.

按标靶查看相关产品

关键词: DOTAP, DOTAP supplier, LNP, lipid, nanoparticles, liposome, transfection, reagent, DNA, RNA, SORT, selective, organ, targeting, 1,2-dioleoyl-3-trimethylammoniumpropane, Lipid, Nanoparticles, Biochemicals, and, Molecular, Biology, 7179, Tocris Bioscience

篇 DOTAP 的引用文献

引用文献是使用了 Tocris 产品的出版物。

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DOTAP 的评论

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DOTAP 实验方案

以下实验方案包含使用 DOTAP（目录编号 7179）的更多信息。