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DSPC

Cat. No. 7943 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： Neutral phospholipid; component of lipid nanoparticles (LNPs)
别名： 1,2-DSPC
化学名： 1,2-Distearoyl-sn-glycero-3-phosphocholine
纯度： ≥95% (HPLC)
说明书
引用文献
评论
实验方案 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for DSPC

DSPC is a phosphatidylcholine, a type of neutral phospholipid with two saturated long-chains (18:0). Commonly used in the generation of micelles, liposomes, lipid nanoparticles (LNPs) and other types of artificial membranes. DSPC is used in formulation of LNPs for nonviral drug delivery systems.

For more information on how to prepare MC3 lipid nanoparticles for RNA delivery, please see our protocol.

技术数据 for DSPC

分子量 790.15
公式 C44H88NO8P
储存 Store at -20°C
纯度 ≥95% (HPLC)
CAS Number 816-94-4
PubChem ID 94190
InChI Key NRJAVPSFFCBXDT-HUESYALOSA-N
Smiles [C@H](OC(CCCCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCCCC)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for DSPC

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
chloroform 79.01 100
ethanol 15.8 20 温和加热

制备储备液 for DSPC

以下数据基于产品分子量 790.15。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 1.27 mL 6.33 mL 12.66 mL
5 mM 0.25 mL 1.27 mL 2.53 mL
10 mM 0.13 mL 0.63 mL 1.27 mL
50 mM 0.03 mL 0.13 mL 0.25 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Dilution Calculator

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参考文献 for DSPC

参考文献是支持产品生物活性的出版物。

Lou et al (2020) Delivery of self-amplifying mRNA vaccines by cationic lipid nanoparticles: The impact of cationic lipid selection. J.Control Release 325 370 PMID: 32619745

Zhang et al (2020) Liver-targeted siRNA lipid nanoparticles treat hepatic cirrhosis by dual antifibrotic and anti-inflammatory activities. ACS Nano 14 6305 PMID: 32378877

If you know of a relevant reference for DSPC, please let us know.

按标靶查看相关产品

关键词: DSPC, DSPC supplier, 1,2-DSPC, DSPC, phosphatidylcholine, micelles, liposomes, lipid, nanoparticles, LNPs, Patisiran, mRNA-1273, Biochemicals, and, Molecular, Biology, Lipid, Nanoparticles, 7943, Tocris Bioscience

篇 DSPC 的引用文献

引用文献是使用了 Tocris 产品的出版物。

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DSPC 的评论

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DSPC 实验方案

以下实验方案包含使用 DSPC（目录编号 7943）的更多信息。