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说明： PEGylated DSPE with azide reactive group
化学名： 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-azido(polyethyleneglycol)-2000]
纯度： ≥90% (HPLC)
生物活性 for DSPE-PEG 2000 Azide
DSPE-PEG 2000 Azide is a functionalized phospholipid-polymer conjugate. It comprises a 1,2-distearoyl-sn-glycero-PE (DSPE) covalently coupled to a linear polyethylene glycol (Mr 2000) with an azide-terminated end for onward chemistry. It is commonly used to synthesize antibody-coupled liposomes and lipid nanoparticles. It has been used to make macrophage and EGFR antibody targeted LNPs using strain-promoted azide alkyne cycloaddition (SPAAC) click reaction.
技术数据 for DSPE-PEG 2000 Azide
| 公式 | (C2H4O)nC44H84N4O10P.NH4 |
| 储存 | Store at -20°C |
| 纯度 | ≥90% (HPLC) |
| CAS Number | 1938081-40-3 |
| PubChem ID | 168311704 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for DSPE-PEG 2000 Azide
| 溶解性 | Soluble to 10 mg/ml in ethanol and to 10 mg/ml in chloroform |
产品说明书 for DSPE-PEG 2000 Azide
参考文献 for DSPE-PEG 2000 Azide
参考文献是支持产品生物活性的出版物。
Zhao et al (2024) Precision treatment of viral pneumonia through macrophage-targeted lipid nanoparticle delivery. Proc.Natl.Acad.Sci.U.S.A. 13 e2314747121 PMID: 38315853
Geisler et al (2024) EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta. J.Control Release 371 455 PMID: 38789090
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关键词: DSPE-PEG 2000 Azide, DSPE-PEG 2000 Azide supplier, immunoliposome, liposome, lipid, nanoparticle, LNP, DSPE, macrophages, SPAAC, Lipid, Nanoparticles, Biochemicals, and, Molecular, Biology, 8837, Tocris Bioscience
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