L-Azidohomoalanine hydrochloride

Cat. No. 6584 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Unnatural amino acid for bio-orthogonal labeling of newly synthesized proteins

化学名： (S)-2-Amino-4-azidobutanoic acid hydrochloride

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for L-Azidohomoalanine hydrochloride

L-Azidohomoalanine hydrochloride is an unnatural amino acid. Incorporated into proteins during de novo protein synthesis, with no effect on protein degradation. Requires methionine-free medium for efficient incorporation. Substrate for wild-type methionyl-tRNA synthetase (MetRS) in vivo. Can be used in BONCAT (bio-orthogonal non-canonical amino acid tagging) for the identification of newly synthesized proteins.

技术数据 for L-Azidohomoalanine hydrochloride

分子量	180.59
公式	C₄H₈N₄O₂.HCl
储存	Store at -20°C
CAS Number	942518-29-8
PubChem ID	147480
InChI Key	NNWQLZWAZSJGLY-VKHMYHEASA-N
Smiles	N[C@H](C(O)=O)CCN=[N+]=[N-].Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for L-Azidohomoalanine hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	18.06	100

制备储备液 for L-Azidohomoalanine hydrochloride

以下数据基于产品分子量 180.59。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	5.54 mL	27.69 mL	55.37 mL
5 mM	1.11 mL	5.54 mL	11.07 mL
10 mM	0.55 mL	2.77 mL	5.54 mL
50 mM	0.11 mL	0.55 mL	1.11 mL

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产品说明书 for L-Azidohomoalanine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for L-Azidohomoalanine hydrochloride

参考文献是支持产品生物活性的出版物。

Dieterich et al (2006) Selective identification of newly synthesized proteins in mammalian cells using bioorthogonal noncanonical amino acid tagging (BONCAT). Proc.Natl.Acad.Sci.U.S.A. 103 9482 PMID: 16769897

Lang & Chin et al (2014) Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins. Chem.Rev. 114 4764 PMID: 24655057

Wang et al (2017) Nonradioactive quantification of autophagic protein degradation with L-azidohomoalanine labeling. Nat.Protoc. 12 279 PMID: 28079880

If you know of a relevant reference for L-Azidohomoalanine hydrochloride, please let us know.

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