L-Azidonorleucine hydrochloride

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说明: Unnatural amino acid for bio-orthogonal or fluorescent labeling of newly synthesized proteins
化学名: (S)-2-Amino-6-azidohexanoic acid hydrochloride
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生物活性 for L-Azidonorleucine hydrochloride

L-Azidonorleucine hydrochloride is an unnatural amino acid; methionine surrogate. Can be incorporated into proteins by a mutant methionyl tRNA synthetase to enable cell-type specific analysis of protein synthesis. For use with bio-orthogonal non-canonical amino-acid tagging (BONCAT) or fluorescent non-canonical amino acid tagging (FUNCAT). Labeling does not affect the normal localization of the labeled proteins.

技术数据 for L-Azidonorleucine hydrochloride

分子量 208.65
公式 C6H12N4O2.HCl
储存 Store at -20°C
CAS Number 1454334-76-9
PubChem ID 121235322
InChI Key RCEAACZNVVRXSJ-JEDNCBNOSA-N
Smiles N[C@H](C(O)=O)CCCCN=[N+]=[N-].Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for L-Azidonorleucine hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 20.86 100

制备储备液 for L-Azidonorleucine hydrochloride

以下数据基于产品分子量 208.65。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 4.79 mL 23.96 mL 47.93 mL
5 mM 0.96 mL 4.79 mL 9.59 mL
10 mM 0.48 mL 2.4 mL 4.79 mL
50 mM 0.1 mL 0.48 mL 0.96 mL

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产品说明书 for L-Azidonorleucine hydrochloride

分析证书/产品说明书
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参考文献 for L-Azidonorleucine hydrochloride

参考文献是支持产品生物活性的出版物。

Alvarez-Castelao et al (2017) Cell-type-specific metabolic labeling of nascent proteomes in vivo. Nat.Biotechnol. 35 1196 PMID: 29106408

Mahdavi et al (2016) Engineered aminoacyl-tRNA synthetase for cell-selective analysis of mammalian protein synthesis. J.Am.Chem.Soc. 138 4278 PMID: 26991063


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关键词: L-Azidonorleucine hydrochloride, L-Azidonorleucine hydrochloride supplier, unnatural, amino, acid, UAA, ANL, methionine, surrogate, BONCAT, FUNCAT, bio-orthogonal, fluorescent, non-canonical, tagging, methionyl, tRNA, synthetase, metRS, Biochemicals, and, Molecular, Biology, Unnatural, Amino, Acids, 6585, Tocris Bioscience

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