Home / Product Type / Fluorescence Imaging / Fluorescent Probes and Stains / Fluorescent Transporter Probes / FFN 102 mesylate

FFN 102 mesylate

Cat. No. 5200 Submit a Review Datasheet / COA / SDS
Pricing Availability   Qty
Description: Selective fluorescent substrate of DAT and VMAT2
Chemical Name: 4-(2-Aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one methanesulfonate
Purity: ≥99% (HPLC)
Datasheet
Citations
Reviews
Literature (1)
Biological Activity Technical Data Solubility Calculators Datasheets References

Biological Activity for FFN 102 mesylate

FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN). Selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.

Licensing Information

Sold with the permission of Columbia University.

Technical Data for FFN 102 mesylate

M. Wt 335.76
Formula C11H11N2ClO3.CH3SO3H
Storage Desiccate at +4°C
Purity ≥99% (HPLC)
CAS Number 1883548-92-2
PubChem ID 91691121
InChI Key ZEZDFYRVIVZPAT-UHFFFAOYSA-N
Smiles ClC1=C(O)C=C(OC(C=C2CCN)=O)C2=C1.CS(=O)(O)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility Data for FFN 102 mesylate

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 6.72 20 with gentle warming
DMSO 33.58 100

Preparing Stock Solutions for FFN 102 mesylate

The following data is based on the product molecular weight 335.76. Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.98 mL 14.89 mL 29.78 mL
5 mM 0.6 mL 2.98 mL 5.96 mL
10 mM 0.3 mL 1.49 mL 2.98 mL
50 mM 0.06 mL 0.3 mL 0.6 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Dilution Calculator

Calculate the dilution required to prepare a stock solution.
x
=
x

Product Datasheets for FFN 102 mesylate

Certificate of Analysis / Product Datasheet
Safety Datasheet

References for FFN 102 mesylate

References are publications that support the biological activity of the product.

Rodriguez et al (2013) Fluorescent DA tracer resolves individual DArgic synapses and their activity in the brain. Proc.Natl.Acad.Sci.U.S.A. 110 870 PMID: 23277566

Sames et al (2013) Visualizing neurotransmitter secretion at individual synapses. ACS Chem.Neurosci. 4 648 PMID: 23862751

Lee et al (2010) Development of pH-responsive fluorescent false neurotransmitters. J.Am.Chem.Soc. 132 8828 PMID: 20540519

If you know of a relevant reference for FFN 102 mesylate, please let us know.

View Related Products by Target

Keywords: FFN 102 mesylate, FFN 102 mesylate supplier, FFN102, mesylate, fluorescent, probes, neurotransmitters, dopamine, transporters, DAT, VMAT2, vesicular, monoamine, false, inhibits, inhibitors, Fluorescent, Substrates, Dopamine, Transporters, Vesicular, Monoamine, Transporter, Probes, 5200, Tocris Bioscience

Citations for FFN 102 mesylate

Citations are publications that use Tocris products.

Currently there are no citations for FFN 102 mesylate. Do you know of a great paper that uses FFN 102 mesylate from Tocris? Please let us know.

Reviews for FFN 102 mesylate

There are currently no reviews for this product. Be the first to review FFN 102 mesylate and earn rewards!

Have you used FFN 102 mesylate?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Literature in this Area

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

*Please note that Tocris will only send literature to established scientific business / institute addresses.

Fluorescent Dyes and Probes Research Product Guide

Fluorescent Dyes and Probes Research Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including dyes for flow cytometry
  • Fluorescent Probes and Stains, including our new MitoBrilliantTM mitochondria stains
  • Tissue Clearing Kits and Reagents
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • TSA VividTM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals