F 127 (20% solution in DMSO)

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说明: Nonionic detergent
别名: Pluronic® F 127 (20% solution in DMSO)
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生物活性 for F 127 (20% solution in DMSO)

F 127 (20% solution in DMSO) is a nonionic detergent used to solubilize large dye molecules and in particular AM esters including BAPTA AM (Cat. No. 2787), and FURA AM (Cat. No. 2220) and ci-IP3/PM (Cat. No. 6210).

Pluronic is a registered trademark of BASF

技术数据 for F 127 (20% solution in DMSO)

储存 Store at RT
CAS Number 9003-11-6
PubChem ID 24751

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for F 127 (20% solution in DMSO)

溶解性 Soluble in DMSO (supplied pre-dissolved in DMSO (20%w/v)

产品说明书 for F 127 (20% solution in DMSO)

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参考文献 for F 127 (20% solution in DMSO)

参考文献是支持产品生物活性的出版物。

Poenie et al (1986) Calcium rises abruptly and briefly throughout the cell at the onset of anaphase. Science 233 886 PMID: 3755550

Drummond et al (1987) Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts. J.Biol.Chem. 262 12801 PMID: 3691669


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关键词: F 127 (20% solution in DMSO), F 127 (20% solution in DMSO) supplier, Pluronic, F127, nonionic, surfactants, detergents, solubilizes, (20%, solution, in, DMSO), Biochemicals, and, Molecular, Biology, 6253, Tocris Bioscience

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F 127 facilitates uniform Fura2 loading in HL1 cells for Ca2+ imaging..
By Anonymous on 12/21/2018
分析类型: In Vivo
种属: Mouse
细胞系/组织: HL-1 Atrial Muscle Cell Line

HL-1 cells were uniformly loaded with Fura-2AM (1 µM), without compartmentalization, in presence of F127 (0.01%) in normal tyrode solution for 40 min.


Pluronic F 127 enhances loading of FURA-2AM in cardiomyocytes.
By Christopher Trummer on 10/15/2018
分析类型: In Vitro
种属: Other
细胞系/组织: primary ventricular cardiomyocytes

Primary guinea pig ventricular cardiomyocytes were loaded with FURA-2AM (1 μM) and Pluronic F 127 (1%) for 30 min followed by washing with normal-Tyrode solution. Cells were stimulated at 1 Hz frequency and fluorescence intensities were measured. Loading of FURA-2AM is better in the presence of Pluronic F 127.

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