Stem Cell Proliferation Other
| Cat. No. | Product Name / Activity |
|---|---|
| 3336 | A 769662 |
| Potent AMPK activator; inhibits MSC proliferation | |
| 2939 | A 83-01 |
| Maintains self-renewal of human iPSCs; selective inhibitor of TGF-βRI, ALK4 and ALK7 | |
| 7001 | AT 7867 |
| Induces proliferation of iPSC-derived pancreatic progenitor cells; pan-Akt and PKA inhibitor | |
| 3194 | BIO |
| Maintains self-renewal and pluripotency of ESCs; potent inhibitor of GSK-3; also inhibits cdks | |
| 7372 | CDK8/19i |
| Potent and selective CDK8 and CDK19 inhibitor; maintains pluripotency of mouse PSCs in culture | |
| 7368 | Cell Counting Kit-8 |
| Cell viability and proliferation assay test solution | |
| 1063 | CGS 21680 hydrochloride |
| Increases proliferation of NPCs; potent A2A receptor agonist | |
| 3858 | CH 223191 |
| AhR antagonist; promotes expansion of human hematopoietic stem cells | |
| 7163 | Chroman 1 |
| Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis | |
| 4027 | 16,16-Dimethyl Prostaglandin E2 |
| Induces stem cell proliferation | |
| 6019 | Diprotin A |
| Increases number of viable HSC during harvesting; DPP-IV inhibitor | |
| 7726 | DMSO, Cell Cryopreserve Grade |
| Intracellular cryoprotective agent | |
| 1261 | EHNA hydrochloride |
| Suppresses spontaneous differentiation of human ESCs; adenosine deaminase inhibitor | |
| 7310 | Emricasan |
| Promotes survival of hPSCs in combination with other small molecules; potent pan-caspase inhibitor | |
| 6340 | Epiblastin A |
| Converts epiblast stem cells to ESCs and promotes ESC self-renewal; CK1 inhibitor | |
| 6961 | FzM1.8 |
| Preserves stemness and promotes proliferation of undifferentiated cells; Frizzled 4 allosteric agonist | |
| 2285 | Go 6983 |
| Optimizes naïve human pluripotent stem cell growth and viability; PKC inhibitor | |
| 2910 | H 89 dihydrochloride |
| Improves survival and clonogenicity of dissociated human ESCs; PKA inhibitor | |
| 4997 | INDY |
| Dyrk1A/B inhibitor; impairs self-renewal of NSCs | |
| 5284 | trans-ISRIB |
| Promotes survival of hPSCs in combination with other small molecules; also integrated stress response (ISR) inhibitor | |
| 3533 | IWP 2 |
| PORCN inhibitor; suppresses self-renewal in R1 ESCs | |
| 7419 | Kyoto Probe-1 |
| Fluorescent probe that selectively identifies undifferentiated iPS/ES cells | |
| 1130 | LY 294002 hydrochloride |
| Prototypical PI 3-kinase inhibitor; suppresses proliferation of mESCs | |
| 6618 | MB 05032 |
| Promotes HSC expansion; also FBPase inhibitor | |
| 1671 | PD 102807 |
| Promotes expansion of erythroid progenitors | |
| 3044 | PD 173074 |
| Selective FGFR1 and -3 inhibitor; inhibits proliferation and differentiation of oligodendrocyte progenitors | |
| 1213 | PD 98059 |
| MEK inhibitor; enhances ESC self-renewal | |
| 4124 | Pioglitazone hydrochloride |
| Acts synergistically with Y-27632 (Cat.No. 1254) to improve PSC cloning efficiency; PPARγ agonist | |
| 7739 | Polyamine Supplement x1000 (lyophilized) |
| Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability | |
| 2296 | Prostaglandin E2 |
| Induces hematopoietic stem cell proliferation | |
| 4978 | Pyrintegrin |
| Enhances survival of human ESCs following enzymatic dissociation | |
| 7723 | RGD peptide |
| Directs association of stem cells with diverse biomaterials; increases cell spreading | |
| 1264 | SB 202190 |
| Promotes stability of human PSCs; potent, selective inhibitor of p38 MAPK | |
| 1202 | SB 203580 |
| Selective inhibitor of p38 MAPK; stimulates neural stem cell proliferation | |
| 1616 | SB 216763 |
| GSK-3 inhibitor; maintains mouse ESCs in a pluripotent state | |
| 1614 | SB 431542 |
| Induces proliferation, differentiation and sheet formation of ESC-derived endothelial cells | |
| 3784 | Sildenafil citrate |
| Promotes mobilization of hematopoietic stem cells (HSCs) in combination with AMD 3100; potent PDE5 inhibitor | |
| 1496 | SP 600125 |
| Used for maintaining stem cells in naive pluripotent state; selective JNK inhibitor | |
| 7086 | StemRegenin 1 |
| Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment | |
| 3300 | SU 5402 |
| Supports mESC self-renewal; potent FGFR and VEGFR inhibitor | |
| 6634 | Surfen |
| Maintains pluripotency of hESCs; heparin sulfate antagonist | |
| 5759 | SW 033291 |
| High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation | |
| 3845 | Thiazovivin |
| Improves survival of hESCs; ROCK inhibitor | |
| 7340 | Tocriscreen Stem Cell Library |
| A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling | |
| 3114 | Troglitazone |
| Selective PPARγ agonist; inhibits growth of hematopoietic cell lines | |
| 1144 | U0126 |
| Regulates hPSCs self-renewal; also potent, selective inhibitor of MEK1 and 2 | |
| 5413 | WH-4-023 |
| Supports self-renewal of naive hESCs | |
| 7791 | WS 6 |
| Induces growth and proliferation of pancreatic islet cells, murine totipotent stem cells, GABAergic neurons and hippocampal neurons | |
| 1254 | Y-27632 dihydrochloride |
| Selective ROCK inhibitor; increases survival rate of human embryonic stem cells undergoing cryopreservation | |
| 7000 | Y-27632 in solution New |
| Sterile-filtered 10 mM solution of Y-27632 pre-dissolved in water | |
| 6599 | Yhhu 3792 |
| Enhances the self-renewal capability of NSCs; notch signaling pathway activator; active in vivo |
Stem Cell Research Product Guide
Our guide highlights the use of small molecules in stem cell research and cell therapy and lists relevant products.
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Our Stem Cells review gives an overview of the use of small molecules in the control of stem cell growth & differentiation and somatic cell reprogramming.
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Developed in-house, this poster summarizes how small molecules have been used in protocols across the stem cell workflow.
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Written by Rebecca Quelch and Stefan Przyborski, this poster summarizes the isolation of pluripotent stem cells, their maintenance in culture, differentiation, and potential uses.
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