Coronavirus Antiviral Other

Cat. No. Product Name / Activity
4274 AP 24534
Identified as targeting human proteins in the SARS-CoV-2 interactome; potent multi-kinase and pan-Bcr-Abl inhibitor
7283 Apilimod dimesylate
Inhibits cellular entry by SARS-CoV-2, MERS-CoV and MHV S pseudovirions; potent and selective PIKfyve inhibitor
7235 Arbidol
Inhibits replication of SARS-CoV-2 in vitro; broad spectrum antiviral
7755 Asunaprevir
Inhibits SARS-CoV-2 Mpro activity; also inhibits hepatitis C virus NS3 protease
3771 Azithromycin
Predicted to disrupt binding of SARS-CoV-2 spike protein to ACE2
7222 Baricitinib
In silico modelling predicts inhibition of SARS-CoV-2 cell entry; highly potent JAK inhibitor
3193 Camostat mesylate
Inhibits entry of SARS-Cov-2 into lung cells; TMPRSS2 inhibitor
4109 Chloroquine diphosphate
Inhibits SARS-CoV-2 infection in vitro
6357 Ciclesonide
Inhibits replication of SARS-CoV-2 in vitro; glucocorticoid
0460 Cinanserin hydrochloride
Inhibits replication of SARS-CoV; Mpro inhibitor and 5-HT2 antagonist
7485 Covidcil-19
Inhibits viral propagation and viral infectivity of SARS-CoV-2
0970 Cycloheximide
Exhibits anti-MERS-CoV activity in vitro; protein synthesis inhibitor
1101 Cyclosporin A
Inhibits coronavirus replication; cyclophilin inhibitor
7223 Dabrafenib mesylate
Targets human proteins in the SARS-CoV-2 interactome; potent and selective B-Raf, CDK16 and NEK9 inhibitor
6793 Dasatinib
Inhibits replication of SARS-CoV and MERS-CoV in vitro; potent pan-Src/Bcr-Abl inhibitor
1467 Daunorubicin hydrochloride
Identified as targeting human proteins in the SARS-CoV-2 interactome; DNA topoisomerase II inhibitor
4583 Digoxin
Exhibits anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor
7336 Dinaciclib
Exhibits antiviral activity against SARS-CoV-2 in vitro; potent and selective inhibitor of CDK2, CDK5, CDK1 and CDK9
3807 Disulfiram
SARS-CoV-2 Mpro inhibitor; also reversibly stimulates SERCA Ca2+-ATPase
4545 E 64d
Inhibts entry of SARS-CoV-2 into lung cells in combination with Camostat (Cat. No. 3193); cathepsin inhibitor
5245 Ebselen
Inhibits SARS-CoV-2 Mpro in vitro; glutathione peroxidase mimic
6986 EG 00229 trifluoroacetate
Inhibits binding of cleaved spike protein of SARS-CoV-2 to neuropilin 1 (NRP1); neuropilin 1 antagonist
7231 EIDD 1931
Inhibits MERS-CoV and SARS-CoV-2 replication in vitro; viral RNA-dependent RNA polymerase (RdRP) inhibitor
7225 Favipiravir
Reduces infection rate of SARS-CoV-2 in vitro; viral RNA polymerase inhibitor
3631 FK 506
Identified as targeting human proteins in the SARS-CoV-2 interactome; potent calcineurin inhibitor
7229 Galidesivir dihydrochloride
Broad spectrum antiviral nucleotide; inhibits coronavirus replication in vitro
3259 Gemcitabine hydrochloride
Inhibits replication of coronaviruses; DNA synthesis inhibitor
7280 GRL 0617
Coronavirus PLpro inhibitor
7227 GS 441524
Displays antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2; viral RNA-dependent RNA polymerase (RdRp) inhibitor; active metabolite of Remdesivir (Cat. No. 7226)
5303 GSK 2194069
Inhibits SARS-CoV-2 infection in vitro; human FASN inhibitor
4618 GW 6471
Blocks SARS-CoV-2 infection in vitro and reduces viral RNA; PPARα antagonist
1416 Homoharringtonine
Inhibits SARS-CoV-2 infection in vitro; inhibits protein synthesis
5648 Hydroxychloroquine sulfate
Inhibits SARS-CoV-2 viral infection in vitro
5906 Imatinib mesylate
Inhibits replication of SARS-CoV and MERS-CoV in vitro; potent and selective v-Abl tyrosine kinase inhibitor
1708 Indomethacin
Identified as targeting human proteins in the SARS-CoV-2 interactome
1260 Ivermectin
Inhibits replication of SARS-Cov-2 in vitro; antiparasitic and antiviral
4499 (+)-JQ1
Inhibits ACE2 and TMPRSS2 transcription and blocks infection by SARS-CoV-2; potent and selective BET bromodomain inhibitor
3765 Linezolid
Identified as targeting human proteins in the SARS-CoV-2 interactome; antibiotic
5213 LL 37
Inhibits interaction between SAR-CoV-2 S1 protein and ACE2; human cathelicidin peptide derivative
0840 Loperamide hydrochloride
Inhibits replication of coronaviruses in vitro; peripherally acting μ opioid agonist and Ca2+ channel blocker
7052 Lopinavir
Inhibits SARS-CoV-2 replication in vitro; highly potent and selective HIV-1 protease inhibitor
7705 Masitinib
SARS-CoV-2 Mpro inhibitor
6819 Mefloquine hydrochloride
Exhibits antiviral activities against SARS-CoV-2; also Cx36 and Cx50 gap channel blocker
2864 Metformin hydrochloride
Identified as targeting human proteins in the SARS-CoV-2 interactome; antidiabetic
7586 Molnupiravir
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
7853 Mpro 13b-H
Negative control for Mpro 13b-K (Cat. No. 7228)
7228 Mpro 13b-K
Coronavirus Mpro inhibitor
7695 Mpro 61
Potent non-covalent inhibitor of SARS-CoV-2 main protease
7230 MPro N3
Coronavirus Mpro inhibitor
3081 Nafamostat mesylate
Inhibits SARS-CoV-2 infection in vitro; serine protease inhibitor
3766 Nelfinavir mesylate
Exhibits anti-MERS-CoV activity in vitro; potent HIV-1 protease inhibitor
4079 Niclosamide
Inhibits SARS-CoV-2 spike protein induced syncytia formation and viral replication in vitro; also STAT3 inhibitor
7234 Nitazoxanide
Inhibits SARS-CoV-2 infection in vitro; Pyruvate flavodoxin/ferredoxin oxidoreductase (PFOR) inhibitor
1076 Ouabain
Exhibits anti-MERS-CoV activity in vitro; Na+/K+ ATPase inhibitor
7505 PLpro inhibitor 19
SARS-CoV-2 PLpro and viral replication inhibitor
7357 PLpro inhibitor 6
SARS-CoV and SARS-CoV-2 PLpro inhibitor
4107 Probenecid
Inhibits SARS-CoV-2 replication and influenza A infection; MRP and OAT3 inhibitor
1125 Quercetin
Inhibits SARS-CoV Mpro; also non-selective PI 3-kinase inhibitor
1292 Rapamycin
Inhibits MERS-CoV infection; mTOR inhibitor and immunosuppressant
7226 Remdesivir
Displays antiviral activity against MERS-CoV, SARS-CoV and SARS-CoV-2; viral RNA-dependent RNA polymerase (RdRp) inhibitor
4501 Ribavirin
Inhibits cytopathic effect of SARS-CoV in vitro; guanosine analog and IMPDH inhibitor
5856 Ritonavir
Improves outcome in an animal model of MERS-CoV infection; HIV protease inhibitor
7064 Ruxolitinib
Targets human proteins in the SARS-CoV-2 interactome; potent and selective JAK1/JAK2 inhibitor
7191 Santacruzamate A
Identified as targeting human host proteins that interact with SARS-CoV-2
7189 Saracatinib
Inhibits MERS-CoV, other coronaviruses and dengue virus
7760 Selinexor
Potent inhibitor of SARS-CoV-2 replication in vitro
7192 SMIP 004
S-phase kinase-associated protein 2 (SKP2) inhibitor; inhibits MERS-CoV replication and induces autophagy in infected cells
7554 SSYA10-001
Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6
1138 Thapsigargin
Inhibits SARS-CoV-2 infection in vitro; SERCA inhibitor
2815 Valproic acid, sodium salt
Identified as targeting human proteins in the SARS-CoV-2 interactome; HDAC inhibitor
0654 Verapamil hydrochloride
Targets human proteins in the SARS-CoV-2 interactome; CaV1.x blocker