All ProductsDisplaying Products Alphabetically by Name (I)
| Cat. No. | Product Name / Activity |
|---|---|
| 7292 | I 432 |
| TMPRSS2 Inhibitor | |
| 4650 | I-BET 151 dihydrochloride |
| BET bromodomain inhibitor; also promotes differentiation of hiPSCs into megakaryocytes | |
| 6521 | I-BET 762 |
| Potent and high affinity BET bromodomain inhibitor; anti-inflammatory; orally bioavailable. | |
| 5591 | I-BRD9 |
| Potent and selective BRD9 inhibitor | |
| 7789 | IA |
| SHAPE-JuMP monoadduct control for TBIA (Cat. No. 7788) | |
| 7015 | IA-Alkyne |
| Broad spectrum cysteine reactive probe | |
| 1066 | IB-MECA |
| A3 selective agonist | |
| 2845 | IBMX |
| PDE inhibitor (non-selective) | |
| 4305 | ICA 069673 |
| KV7.2/KV7.3 channel opener | |
| 4950 | ICA 110381 |
| KV7.2/7.3 activator; displays anticonvulsant properties | |
| 5066 | ICA 121431 |
| Potent and selective NaV1.3 and NaV1.1 channel blocker | |
| 4505 | ICG 001 |
| Inhibits TCF/β-catenin-mediated transcription | |
| 7749 | ICG-d7 |
| Near-infrared (NIR) fluorescent dye; partially deuterated form of Indocyanine Green (Cat. No. 7510), suitable for in vivo imaging. | |
| 0821 | ICI 118,551 hydrochloride |
| Highly selective β2 inverse agonist | |
| 0820 | ICI 174,864 |
| δ selective peptide antagonist | |
| 1047 | ICI 182,780 |
| Estrogen receptor antagonist | |
| 0778 | ICI 199,441 hydrochloride |
| Potent κ agonist | |
| 0822 | ICI 204,448 hydrochloride |
| κ agonist, acts peripherally | |
| 4015 | IDE 1 |
| Induces definitive endoderm formation in mouse and human ESCs | |
| 7866 | IDR 1002 |
| Innate defence regulator peptide | |
| 1636 | IEM 1460 |
| Open-channel blocker of AMPA currents; selective for non-GluA2-containing receptors | |
| 4198 | IEM 1925 dihydrobromide |
| Voltage- and use-dependent open-channel AMPA blocker | |
| 5554 | IHR 1 |
| Potent Smo antagonist | |
| 2539 | IKK 16 |
| Selective inhibitor of IKK | |
| 2611 | IMD 0354 |
| Inhibitor of IKKβ; also exhibits antibacterial activity | |
| 6016 | IN 1130 |
| Potent and selective inhibitor of TGF-βRI | |
| 2162 | INCA-6 |
| Inhibitor of calcineurin-substrate association | |
| 6007 | INCB 024360-analog |
| Potent indoleamine 2,3-dioxygenase (IDO) inhibitor | |
| 4306 | INCB 3284 dimesylate |
| Selective CCR2 antagonist | |
| 7685 | IND 1316 |
| AMPK activator | |
| 4997 | INDY |
| DYRK1A/B inhibitor | |
| 6341 | INF 39 |
| Irreversible NLRP3 inhibitor | |
| 6172 | INF 4E |
| Caspase-1 and NLRP3 inflammasome inhibitor | |
| 7870 | ING-2 AM |
| Fluorescent sodium ion (Na+) indicator, membrane permeable | |
| 7423 | INT 131 |
| PPARγ partial agonist | |
| 4464 | IOX 1 |
| Histone demethylase inhibitor; cell permeable | |
| 4451 | IOX 2 |
| Potent, selective HIF-1α prolyl hydroxylase-2 (PHD2) inhibitor | |
| 5699 | IP7e |
| Potent Nurr1 activator | |
| 3622 | IPA 3 |
| Group I PAK inhibitor | |
| 7871 | IPG-4 AM |
| Fluorescent potassium ion (K+) indicator, membrane permeable | |
| 3429 | 4-IPP |
| Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate | |
| 5509 | IPTG |
| Used in cloning procedures with X-GAL | |
| 5665 | IRAK1/4 Inhibitor I |
| IRAK4 and IRAK1 inhibitor | |
| 7983 | IRAK3 Degrader 23 |
| IRAK3 Degrader (PROTAC® | |
| 4288 | ISO 1 |
| Macrophage migration inhibitory factor (MIF) inhibitor | |
| 5284 | trans-ISRIB |
| Integrated stress response (ISR) inhibitor | |
| 4439 | ISX 9 |
| Neurogenic agent; induces neuronal differentiation of SVZ progenitors and also induces cardiomyogenic differentiation | |
| 4596 | IT1t dihydrochloride |
| Potent CXCR4 antagonist | |
| 5068 | ITD 1 |
| Selective inhibitor of TGF-β signaling; induces cardiomyocyte differentiation in ESCs | |
| 1803 | ITE |
| Endogenous agonist for the transcription factor aryl hydrocarbon receptor | |
| 5692 | ITH 12575 |
| Mitochondrial Na+/Ca2+ exchange (mNCX) inhibitor | |
| 5279 | IWP 12 |
| Potent PORCN inhibitor; active in vivo | |
| 3533 | IWP 2 |
| PORCN inhibitor; inhibits Wnt processing and secretion | |
| 5214 | IWP 4 |
| Potent inhibitor of Wnt/β-catenin signaling | |
| 4992 | IWP L6 |
| Potent PORCN inhibitor | |
| TB3532-RMU | endo-IWR 1 |
| endo-IWR 1 synthesized to Ancillary Material Grade | |
| 3532 | endo-IWR 1 |
| Wnt/β-catenin signaling inhibitor; axin stabilizer | |
| 1086 | Iberiotoxin |
| KCa (BK) channel blocker | |
| 0285 | Ibotenic acid |
| NMDA agonist; also non selective mGlu agonist | |
| 6813 | Ibrutinib |
| Potent and selective BTK inhibitor | |
| 1694 | Ibudilast |
| PDE inhibitor (non-selective) | |
| 3908 | Ibutilide hemifumarate |
| Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic | |
| 1531 | Icilin |
| Activates cold receptors. Cooling agent | |
| 6904 | Idasanutlin |
| Potent MDM2 inhibitor; inhibits MDM2-p53 interaction | |
| 7631 | Idelalisib |
| Potent PI 3-Kinase δ isoform inhibitor | |
| 0545 | Ifenprodil hemitartrate |
| Non-competitive NMDA antagonist; also σ ligand | |
| 2332 | (+)-Igmesine hydrochloride |
| Selective σ1 ligand; antidepressant | |
| 5906 | Imatinib mesylate |
| Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit | |
| 0729 | Imetit dihydrobromide |
| Standard H3 and H4 agonist (H3 > H4) | |
| 0986 | Imiloxan hydrochloride |
| Highly selective α2B antagonist | |
| 7841 | Imipramine hydrochloride |
| Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment | |
| 3700 | Imiquimod |
| Toll-like receptor 7 (TLR7) agonist | |
| 0932 | Immepip dihydrobromide |
| Standard H3 agonist. Also H4 agonist | |
| 1588 | Indatraline hydrochloride |
| Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake | |
| 3728 | Indibulin |
| Microtubule destabilizer | |
| 7196 | Indinavir sulfate |
| Potent and selective HIV-1 and HIV-2 protease inhibitor | |
| 6782 | Indisulam |
| Molecular glue; pre-mRNA splicing modulator | |
| 6704 | Indo 1AM |
| Fluorescent Ca2+ indicator | |
| 7510 | Indocyanine green |
| Near-infrared (NIR) fluorescent dye; suitable for in vivo imaging | |
| 1708 | Indomethacin |
| Cyclooxygenase inhibitor (COX-1 > COX-2) | |
| 1482 | D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt |
| Ca2+ mobilizing second messenger | |
| 3435 | Insulin (human) recombinant, expressed in yeast |
| Endogenous peptide agonist | |
| 0737 | 2-Iodomelatonin |
| High affinity melatonin agonist | |
| 0779 | Iodophenpropit dihydrobromide |
| Potent, selective H3 antagonist | |
| 1745 | 5-Iodotubercidin |
| Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases | |
| 0307 | (S)-(-)-5-Iodowillardiine |
| Highly potent and subtype-selective kainate agonist | |
| 1704 | Ionomycin calcium salt |
| Calcium ionophore | |
| 2092 | Ionomycin free acid |
| Calcium ionophore | |
| 1869 | Ipsapirone |
| Selective 5-HT1A agonist | |
| 5798 | Irbesartan |
| Potent AT1 antagonist | |
| 3000 | Iressa |
| Orally active, selective EGFR inhibitor | |
| 4695 | Ischemin sodium salt |
| CBP inhibitor; cell permeable | |
| 6483 | Isoginkgetin |
| Pre-mRNA splicing inhibitor; cell permeable | |
| 0235 | Isoguvacine hydrochloride |
| Selective GABAA agonist | |
| 1747 | Isoproterenol hydrochloride |
| Standard selective β agonist | |
| 5408 | Ispinesib |
| High affinity and selective allosteric KSP inhibitor | |
| 2004 | Isradipine |
| CaV1.x blocker | |
| 5147 | Istradefylline |
| Potent and selective A2A antagonist | |
| 5981 | Itraconazole |
| SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623) | |
| 6542 | Ivabradine hydrochloride |
| HCN channel blocker; inhibits If pacemaker current | |
| 7887 | Ivacaftor |
| Potent and selective CFTR potentiator | |
| 1260 | Ivermectin |
| Positive allosteric modulator of α7 nAChRs; also positive allosteric modulator of P2X4 receptors | |
| 7761 | Ivosidenib |
| Potent inhibitor of mutant isocitrate dehydrogenase (mIDH1) |
Tocris Products by Catalog Number
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