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Displaying Products Alphabetically by Name (M)

Cat. No. Product Name / Activity
5807 M 084 hydrochloride
TRPC4 and TRPC5 inhibitor; antidepressant and anxiolytic
1941 m-3M3FBS
Phospholipase C activator
1942 o-3M3FBS
Inactive analog of m-3M3FBS (Cat. No. 1941)
3425 M40
Potent, non-selective galanin receptor antagonist
7754 M4K2163 dihydrochloride
Potent and selective ALK2 inhibitor
2697 M617
Selective GAL1 agonist
5324 M8 B hydrochloride
Potent and selective TRPM8 channel blocker
2698 M871
Selective GAL2 antagonist
6618 MB 05032
Potent FBPase inhibitor; promotes HSC expansion
4077 MC 1568
Selective HDAC class IIa inhibitor
5727 MC 1742
Potent class I and IIb HDAC inhibitor
3806 MCH (human, mouse, rat)
Potent endogenous MCH agonist
0336 (RS)-MCPG
Non-selective mGlu antagonist
3696 (RS)-MCPG disodium salt
Non-selective mGlu antagonist; disodium salt of (RS)-MCPG (Cat. No. 0336)
0337 (S)-MCPG
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
7195 MCU i4
Negative modulator of mitochondrial Ca2+ uniporter (MCU)
7503 MD13
Potent MIF Degrader (PROTAC®)
7504 MD15
Negative control for MD13 (Cat. No. 7503)
4173 MDL 100907
Potent and selective 5-HT2A antagonist
0870 MDL 11,939
5-HT2A antagonist
0640 MDL 72222
5-HT3 antagonist
5887 MES, free acid
Commonly used buffer
6718 ±-MF 094
Selective USP30 inhibitor
1748 MG 132
Proteasome and calpain inhibitor. Inhibits NF-κB activation
6033 (R)-MG 132
Potent 20S proteasome inhibitor
5604 MI 14
Potent and selective PI 4-kinase IIIβ inhibitor
4848 MI 2 (MALT1 inhibitor)
MALT1 inhibitor
3362 MIRA-1
Restores mutant p53 activity; proapoptotic
5272 MK 0677
High affinity ghrelin receptor agonist
4622 MK 1903
Potent and selective GPR109A (HCA2) agonist
0941 MK 212 hydrochloride
5-HT2C agonist
7850 MK 2206 dihydrochloride
Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor
5842 MK 386
Potent, selective human type 1 5α-reductase inhibitor
2338 MK 571
Potent CysLT1 (LTD4) inverse agonist. Also MRP1 inhibitor
0924 (+)-MK 801 maleate
Non-competitive NMDA antagonist; acts at ion channel site
0955 (-)-MK 801 maleate
NMDA antagonist; less active enantiomer of (+)-MK 801
1311 MK 886
Inhibitor of 5-lipoxygenase-activating protein (FLAP)
5547 MK6-83
TRPML channel activator
4621 MKT 077
Binds mot-2; selectively cytotoxic in cancer cells
4854 ML 00253764 hydrochloride
Melanocortin MC4 receptor antagonist; brain penetrant
4899 ML 120B dihydrochloride
Novel IKK2-selective inhibitor
4549 ML 133 hydrochloride
Kir2 channel blocker
4266 ML 141
Selective Cdc42 Rho family inhibitor
4172 ML 145
GPR35 antagonist
7821 ML 162
Inhibits glutathione peroxidase (GPX4); induces ferroptosis
4957 ML 179
Selective liver receptor homolog 1 (LRH1) inverse agonist
6668 ML 184
Selective GPR55 agonist; also promotes NSC proliferation and differentiation
4866 ML 190
Selective κ opioid receptor antagonist
4860 ML 193
Potent, selective GPR55 antagonist
4732 ML 204
Selective TRPC4 inhibitor
5987 (±)-ML 209
RORγt inverse agonist; suppresses Th17 cell differentiation
6429 ML 210
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis
4519 ML 213
KV7.2 and KV7.4 channel opener
4507 ML 218 hydrochloride
CaV3.x blocker
4748 ML 221
Apelin antagonist
5966 ML 233
Non-peptide apelin agonist
4829 ML 239
Breast cancer stem cell inhibitor
5153 ML 240
ATP-competitive inhibitor of p97 ATPase
4687 ML 252
Potent and selective KV7.2 inhibitor; brain penetrant
4777 ML 277
Selective KV7.1 (KCNQ1) potassium channel activator; augments IKs current
4880 ML 281
STK33 inhibitor
5380 ML 297
Selective Kir3.1/3.2 (GIRK1/2) channel activator
4894 ML 299
Potent inhibitor of PLD1 and PLD2; CNS penetrant
5700 ML 315 hydrochloride
Inhibitor of Clk and DYRK kinases
6435 ML 323
Potent and selective USP1-UAF1 allosteric inhibitor
5625 ML 334
Inhibitor of Keap1- Nrf2 interaction
6887 ML 335
Selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) activator
4982 ML 337
Selective negative allosteric modulator of mGlu3 receptors
5943 ML 339
Potent and selective hCXCR6 antagonist
4945 ML 347
Potent and selective ALK1 and ALK2 inhibitor
6448 ML 351
Selective 12/15 LOX inhibitor; active in vivo
5337 ML 365
Potent and selective K2P3.1 (TASK-1) channel blocker
5738 ML 382
MRGPRX1 positive allosteric modulator
6243 ML 385
Nrf2 inhibitor; phenotypically lethal
6889 ML 418
Kir 7.1 inhibitor; also inhibits Kir 6.2
6886 ML 67-33
K2P2.1 (TREK-1), K2P10.1 (TREK-2) and K2P4.1 (TRAAK) channel activator
4310 ML 7 hydrochloride
Selective inhibitor of myosin light chain kinase
0431 ML 9 hydrochloride
Myosin light chain kinase inhibitor
4746 ML SA1
Activator of TRPML channels
8119 ML T7
Inhibitor of phosphatidylserine/CEACAM1 binding to Tim-3
1885 MLCK inhibitor peptide 18
Selective inhibitor of myosin light chain kinase
3345 MLN 4760
Potent and selective angiotensin-converting enzyme 2 (ACE2) inhibitor
6499 MLN 4924
Potent and selective NEDD8 activating enzyme (NAE) inhibitor; cell permeable
4582 MLR 1023
Selective allosteric activator of Lyn kinase
6171 MLS 1547
G protein-biased D2 partial agonist
5756 MLi-2
Potent and selective LRRK2 inhibitor
5307 MM 102
Potent WDR5/MLL interaction inhibitor
3822 MM 11253
RARγ-selective antagonist
5992 MM 54
Potent apelin antagonist
6858 MMG 11
TLR2 antagonist
4388 MNI 137
Selective negative allosteric modulator of group II mGlu receptors
1490 MNI-caged-L-glutamate
Stable photoreleaser of L-glutamate
6871 MO-I-500
FTO inhibitor; anticonvulsant
2568 MOG (35-55)
Encephalitogenic myelin oligodendrocyte glycoprotein fragment
7926 MOMBA
Selective orthostatic agonist of hFFA2-DREADDs
5770 MONNA
Potent TMEM16A (Anoctamin-1) blocker
8802 MPD 2
SARS-CoV-2 Mpro Degrader (PROTAC®)
1212 MPEP hydrochloride
Potent mGlu5 antagonist; also positive allosteric modulator of mGlu4 receptors
1991 MPP dihydrochloride
Highly selective ERα antagonist
7695 Mpro 61
Potent non-covalent inhibitor of SARS-CoV-2 main protease
7230 MPro N3
Coronavirus Mpro inhibitor
7856 MQAE
Fluorescent Cl- indicator; membrane permeable
8122 MR 24
Potent and selective MST3 kinase binding inhibitor
3817 MRK 016
α5-selective GABAA inverse agonist
4000 MRK 560
γ-secretase inhibitor; attenuates amyloid plaque deposition
1217 MRS 1220
Highly potent and selective hA3 antagonist
1385 MRS 1334
Potent, highly selective hA3 antagonist
2752 MRS 1754
Selective A2B antagonist
0900 MRS 2179 tetrasodium salt
Selective P2Y1 antagonist
2402 MRS 2211
Competitive P2Y13 antagonist
2157 MRS 2365
Highly potent and selective P2Y1 agonist
2159 MRS 2500 tetraammonium salt
Highly potent and selective P2Y1 antagonist
2146 MRS 2578
Selective P2Y6 antagonist
2915 MRS 2690
Potent P2Y14 agonist
2502 MRS 2693 trisodium salt
Selective P2Y6 agonist
3884 MRS 2768 tetrasodium salt
Selective P2Y2 agonist
5633 MRS 2905
Potent and selective P2Y14 receptor agonist
4261 MRS 4062 triethylammonium salt
Selective P2Y4 receptor agonist
5134 MRT 67307 dihydrochloride
Salt inducible kinase (SIK) inhibitor; also ULK1 and 2 inhibitor
5067 MRT 68601 hydrochloride
Potent TBK inhibitor
5780 MRT 68921 dihydrochloride
ULK inhibitor
7488 MRTX 849
Mutation-selective inhibitor of KRASG12C
5713 MS 023 dihydrochloride
Potent and selective type I PRMT inhibitor
8077 MS 147
PRC1 Degrader (PROTAC®); degrades BMI1 and RING1B
7395 MS 154
Potent and selective cereblon-recruiting Degrader (PROTAC®) of mutant EGFR
7396 MS 154N
Negative control for MS 154 (Cat No. 7395)
8079 MS 159
NSD2 Degrader (PROTAC®)
6298 MS 21570
GPR171 antagonist
6208 MS 275
HDAC (Class I) inhibitor
8076 MS 28
Cyclin D1, CDK4/6 and cyclin D3 Degrader (PROTAC®)
7397 MS 39
Potent and selective VHL-recruiting Degrader (PROTAC®) of mutant EGFR
7398 MS 39N
Negative control for MS 39 (Cat. No. 7397)
8080 MS 4322
Selective PRMT5 Degrader (PROTAC®)
8073 MS 6105
Potent lactate dehydrogenase Degrader (PROTAC®)
7353 MSA 2
Non-nucleotide STING agonist; orally bioavailable
7927 MSC 1186
Potent and selective SRPK family inhibitor
5641 MSC 2032964A
Potent and selective ASK1 inhibitor; orally bioavailable
8008 MSC 4381
Potent and selective monocarboxylate transporter 4 (MCT4) inhibitor
3013 [Nle4,D-Phe7]-α-MSH
Melanocortin receptor agonist
2584 α-MSH
Endogenous melanocortin receptor agonist
0803 MSOP
Specific group III mGlu antagonist
2921 MTEP hydrochloride
Potent and selective mGlu5 antagonist
7980 MTK 458
PINK1 activator
5224 MTT
Reagent used in the measurement of cell proliferation
7979 MU 1742
Potent and selective CK1α, CK1δ and CK1ε inhibitor
8109 MYX 1715
N-myristoyltransferase (NMT) inhibitor
6154 MZ 1
(+)-JQ1 based Degrader (PROTAC®) that preferentially degrades BRD4
7855 Mag-Fura-2 AM
Magnesium (Mg2+) indicator, membrane permeable
7681 Mandi
Highly efficient chemical inducer of proximity (CIP)
6856 α-Mangostin
Inhibits proliferation and induces apoptosis selectively in pancreatic CSCs and cancer cell lines
3756 Maraviroc
Selective CCR5 antagonist
2631 Marimastat
Broad spectrum MMP inhibitor
7705 Masitinib
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor
4949 MaxiPost
Potassium channel modulator; exerts subtype-specific effects
1384 McN-A 343
Selective M1 muscarinic agonist
3982 Mdivi 1
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis
7634 Me VH 032, amine
Amine functionalized VHL ligand for PROTAC® research
3873 MeBIO
Inactive analog of BIO (Cat. No. 3194)
2281 2'-MeCCPA
Highly selective and potent A1 receptor agonist
2843 Mecamylamine hydrochloride
Non-competitive nAChR antagonist
4245 Meclizine dihydrochloride
Human pregnane X receptor agonist; H1 antagonist
5160 Medetomidine hydrochloride
Potent and highly selective α2 agonist
6819 Mefloquine hydrochloride
Cx36 and Cx50 gap channel blocker; also antimalarial and antischistosomal
6285 Megestrol Acetate
Synthetic progesterone analog
2566 Melanotan II
High affinity melanocortin receptor agonist
3550 Melatonin
Endogenous hormone; agonist at MT1 and MT2
1193 Melittin
Inhibits Gs and stimulates Gi activity
0773 Memantine hydrochloride
NMDA antagonist; acts at ion channel site
0660 Mepyramine maleate
Selective H1 inverse agonist
7577 3-Mercaptopicolinic acid hydrochloride
Phospoenolpyruvate carboxykinase (PEPCK) inhibitor; inhibits gluconeogenesis
3053 Mesopram
Orally active PDE4 inhibitor
1644 Mesulergine hydrochloride
5-HT2A and 5-HT2C antagonist; also D2-like partial agonist
1443 Metastin (human)
Potent, endogenous ligand for kisspeptin receptor
2864 Metformin hydrochloride
Activator of LKB1/AMPK; antidiabetic agent
1230 Methotrexate
Cytotoxic agent
4920 Methoxy-X04
Brain penetrant fluorescent amyloid β probe. Used for: detection and quantification of plaques, tangles and cerebrovascular amyloid. Application: confocal microscopy, suitable for in vivo imaging
7320 Methoxyluteolin
Inhibitor of pro-inflammatory mediator release from mast cells
5698 1-Methyl-D-tryptophan
Indoleamine 2,3-dioxygenase (IDO) inhibitor
3977 3-Methyladenine
Class III PI 3-kinase inhibitor; also inhibits autophagy
3209 α,β-Methyleneadenosine 5'-triphosphate trisodium salt
Non-selective P2 agonist
0549 Methylergometrine maleate
Active metabolite of methysergide (Cat. No. 1064)
0569 (R)-(-)-α-Methylhistamine dihydrobromide
Potent, standard H3 agonist
2342 4-Methylhistamine dihydrochloride
Selective, high affinity H4 agonist
1029 Methyllycaconitine citrate
Selective α7 neuronal nAChR antagonist
4979 Methylmalonate
Succinate dehydrogenase inhibitor
4819 Methylprednisolone
Glucocorticoid receptor agonist
3017 1-Methylpsilocin
Potent and selective 5-HT2C agonist
1624 2-Methylthioadenosine diphosphate trisodium salt
Potent agonist at P2Y1, P2Y12 and P2Y13
1062 2-Methylthioadenosine triphosphate tetrasodium salt
Non-selective P2 agonist
1064 Methysergide maleate
5-HT1/5-HT2 antagonist
3256 Metoprolol tartrate
Selective β1 antagonist
3292 Metyrapone
11-β hydroxylase inhibitor
1526 Mevastatin
HMG-CoA reductase inhibitor
2596 Mexiletine hydrochloride
Na+ channel blocker; antiarrhythmic agent
2198 Mibefradil dihydrochloride
CaV3.x blocker
2832 Midazolam hydrochloride
Benzodiazepine agonist
1479 Mifepristone
Progesterone and glucocorticoid receptor antagonist
3117 Miglustat hydrochloride
α-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity
1504 Milrinone
PDE3 inhibitor
3268 Minocycline hydrochloride
Antibiotic. Displays neuroprotective effects
0583 Minoxidil
Kir6 channel (KATP) opener
7070 Mirabegron
Potent and selective β3 agonist
3190 Mirin
MRN-ATM pathway inhibitor
7091 Miro1 Reducer
Promotes mitochondrial Rho GTPase 1 (Miro1) degradation
2018 Mirtazapine
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
1489 Mithramycin A
Inhibitor of DNA and RNA polymerase
7641 Mito-HE
Red-fluorescent mitochondrial superoxide indicator. Used for: live cell imaging. Application: confocal microscopy, flow cytometry
7700 MitoBrilliant™ 646
Universal red fluorescent mitochondrial stain for both live and fixed cells
7693 MitoBrilliant™ Live 549
Orange fluorescent mitochondrial stain for live cells, Δψm dependent
7417 MitoBrilliant™ Live 646
Red fluorescent mitochondrial stain for live cells, Δψm dependent
4428 MitoPY1
Fluorescent mitochondrial hydrogen peroxide indicator. Used for: live cell imaging. Application: confocal microscopy
3258 Mitomycin C
DNA cross-linking antitumor agent
4395 Moclobemide
Reversible MAO-A inhibitor
1811 Modafinil
Psychostimulant
7586 Molnupiravir
Prodrug of antiviral nucleoside analog; inhibits SARS-CoV, SARS-CoV-2 and MERS-CoV infection
1305 Monastrol
Selective inhibitor of mitotic kinesin Eg5
5904 Montelukast sodium
CysLT1 and GPR17 antagonist
5158 Morphine hydrochloride
Narcotic opioid analgesic
2264 Motilin (human, porcine)
Endogenous peptide regulator of gastrointestinal motility
7853 Mpro 13b-H
Negative control for Mpro 13b-K (Cat. No. 7228)
7228 Mpro 13b-K
Coronavirus Mpro inhibitor
8126 Mpro Tracer
SARS-CoV-2 main protease fluorescent ligand; TR-FRET acceptor
5142 Mps1-IN-1 dihydrochloride
Selective Mps1 kinase inhibitor
3074 (+)-Muscarine iodide
Muscarinic receptor agonist
0289 Muscimol
Potent GABAA agonist; also GABAA-ρ partial agonist
4102 Mycophenolate mofetil
Inosine monophosphate dehydrogenase (IMPDH) inhibitor
1505 Mycophenolic acid
Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

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