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Displaying Products Alphabetically by Name (S)

Cat. No. Product Name / Activity
5568 S 18886
Potent thromboxane A2 (TP) antagonist
5714 S 2101
LSD1 inhibitor
3518 S 24795
α7 nAChR partial agonist
5577 S4
High affinity and selective CA IX and CA XII inhibitor
8050 SA-15-P
Dual inhibitor of LAG3 interaction with both MHCII and FGL1
4951 SA 4503 dihydrochloride
Selective σ1 receptor agonist
4366 SAG
Potent Smoothened receptor agonist; activates the Hedgehog signaling pathway
5282 SAG 21k
Hedgehog signaling activator; brain penetrant and orally bioavailable
6390 SAG dihydrochloride
Dihydrochloride salt of SAG; Smo receptor agonist
4652 SAHA
Class I and II HDAC inhibitor
7970 SAHA-FITC
Fluorescent HDAC1/2 probe; suitable for use in TR-FRET and FP assays
6477 SAHM1
Notch pathway inhibitor; prevents Notch complex assembly
6239 SAK 3
Potent CaV3.1 and 3.3 activator; orally bioavailable
1974 SANT-1
Inhibitor of hedgehog (Hh) signaling; antagonizes smoothened activity
5831 SAR 7334
Potent TRPC6 inhibitor
1264 SB 202190
Potent, selective inhibitor of p38 MAPK
1202 SB 203580
Selective inhibitor of p38 MAPK
1402 SB 203580 hydrochloride
Selective inhibitor of p38 MAPK; water-soluble
1372 SB 204741
Potent, selective 5-HT2B antagonist
4962 SB 204990
ATP citrate lyase (ACLY) inhibitor
0921 SB 205607 dihydrobromide
Selective, high affinity non-peptide δ1 agonist
1661 SB 206553 hydrochloride
Potent and selective 5-HT2B and 5-HT2C antagonist; orally active
1242 SB 216641 hydrochloride
Selective h5-HT1B antagonist
1616 SB 216763
Potent, selective GSK-3 inhibitor
2560 SB 218078
Chk1 inhibitor
1393 SB 222200
Potent, selective non-peptide NK3 antagonist. Brain penetrant
1221 SB 224289 hydrochloride
Selective 5-HT1B antagonist
2725 SB 225002
Potent and selective CXCR2 antagonist
1962 SB 239063
Potent, selective p38 MAPK inhibitor; orally active
8010 SB 24011
Inhibitor of STING-TRIM29 interaction; increases cellular STING levels
2901 SB 242084
Selective 5-HT2C antagonist; brain penetrant
1961 SB 258585 hydrochloride
Potent, selective 5-HT6 antagonist
2726 SB 258719 hydrochloride
Selective 5-HT7 antagonist
2724 SB 265610
Potent CXCR2 antagonist
1612 SB 269970 hydrochloride
Potent and selective 5-HT7 antagonist; brain penetrant
3368 SB 271046 hydrochloride
Selective 5-HT6 antagonist; orally active
4207 SB 277011A dihydrochloride
Selective D3 antagonist
6860 SB 290157 trifluoroacetate
Potent C3a receptor antagonist
4213 SB 297006
Potent and selective CCR3 antagonist
3650 SB 328437
Potent and selective CCR3 antagonist
5671 SB 332235
Potent CXCR2 antagonist
1960 SB 334867
Selective non-peptide OX1 antagonist
1615 SB 366791
Potent and selective TRPV1 competitive antagonist
3189 SB 399885 hydrochloride
Potent and selective 5-HT6 antagonist
6088 SB 3CT
High affinity and selective MMP2 inhibitor
6881 SB 4
Potent BMP4 agonist
1963 SB 408124
Selective non-peptide OX1 antagonist
1617 SB 415286
Potent, selective GSK-3 inhibitor
TB1614-GMP SB 431542
SB 431542 synthesized to cGMP guidelines
3263 SB 505124
Selective inhibitor of TGF-βRI, ALK4 and ALK7
3211 SB 525334
Selective inhibitor of TGF-βRI
2650 SB 590885
Potent B-Raf inhibitor
3573 SB 612111 hydrochloride
Selective NOP antagonist
4673 SB 674042
Potent and selective non-peptide OX1 antagonist
3188 SB 699551
Selective 5-ht5a antagonist
5040 SB 706504
p38 MAPK inhibitor
4630 SB 747651A dihydrochloride
Potent MSK1 inhibitor; also inhibits other AGC group kinases
4118 SB 772077B dihydrochloride
Potent Rho-kinase inhibitor; vasodilator
4963 SC 144 hydrochloride
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
1206 SC 19220
Selective EP1 receptor antagonist
4189 SC 26196
Selective fatty acid desaturase 2 inhibitor
2791 SC 51322
Potent EP1 receptor antagonist
1550 SC 560
Cyclooxygenase-1 (COX-1) inhibitor
3919 SC 236
Selective cyclooxygenase-2 (COX-2) inhibitor
4635 SC 79
Akt activator
1400 SCH 202676 hydrobromide
Inhibitor of ligand binding to G-protein-coupled receptors
3240 SCH 221510
Potent and selective NOP agonist
0925 SCH 23390 hydrochloride
Selective D1-like antagonist; also 5-HT2C agonist and Kir3 channel blocker
1690 SCH 28080
H+,K+-ATPase inhibitor
5815 SCH 336
Highly potent and selective CB2 inverse agonist
2299 SCH 39166 hydrobromide
High affinity D1-like antagonist
2463 SCH 442416
Very selective, high affinity A2A antagonist
0984 SCH 50911
Selective and competitive GABAB antagonist; orally bioavailable
2270 SCH 58261
Potent, highly selective A2A antagonist
1592 SCH 79797 dihydrochloride
Potent, selective non-peptide PAR1 antagonist
3528 SCIO 469 hydrochloride
Selective p38 MAPK inhibitor
7900 SCOTfluor 510 Fmoc-Dapa-OH
Fmoc protected fluorescent amino acid for use in solid-phase peptide synthesis to prepare PAINT imaging probes
7446 SCOTfluor 510, fluoro
Amine-reactive fluorescent probe precursor
7447 SCOTfluor glucose probe 510
Fluorescent glucose probe
7448 SCOTfluor lactic acid probe 510
Fluorescent lactic acid probe
5342 SCR7 pyrazine
Enhances HDR efficiency
3035 SD 1008
JAK2/STAT3 signaling pathway inhibitor
3269 SD 208
Potent ATP-competitive TGF-βRI inhibitor
4775 SD 2590 hydrochloride
Potent MMP inhibitor
2394 SDZ NKT 343
Highly selective human NK1 antagonist
2465 SDZ WAG 994
Potent and selective A1 agonist
6979 SEN 177
Potent glutaminyl cyclase inhibitor; disrupts binding of SIRP-α to CD47
6990 SET 2
Selective TRPV2 antagonist
2284 SEW 2871
Cell-permeable, selective S1P1 receptor agonist
3898 SF 11
NPY Y2 receptor antagonist
5020 SF 1670
PTPN2 and PTEN inhibitor
4541 SGC 0946
Highly potent and selective DOT1L inhibitor; cell permeable
6825 SGC 3027
Potent and selective PRMT7 inhibitor
6838 SGC 3027N
Negative control for SGC 3027 (Cat. No. 6825)
7182 SGC 6870
Potent and selective PRMT6 allosteric inhibitor
7184 SGC 6870N
Negative control for SGC 6870 (Cat. No. 7182)
5367 SGC 707
Potent and selective allosteric inhibitor of PRMT3
6528 SGC AAK1 1
AAK1 and BMP2K inhibitor; activates Wnt signaling
6529 SGC AAK1 1N
Negative control for SGC AAK1 1 (Cat.No. 6528)
7450 SGC CK2-1
Potent CK2A2 and CK2A1 inhibitor; also inhibits DYRK2
6564 SGC GAK 1
High affinity cyclin G associated kinase (GAK) inhibitor
7460 SGC SMARCA-BRDVIII
Potent and selective SMARCA2/4 and PB1(bromo 5)-selective SWI/SNF bromodomain inhibitor
4889 SGC-CBP30
Potent CBP/p300 BRD inhibitor
5356 SGX 523
Selective and potent c-MET kinase inhibitor
4510 SHA 68
Selective Neuropeptide S receptor antagonist
6998 SHIN 1
Potent SHMT inhibitor
3420 SHU 9119
MC3 and MC4 antagonist; MC5 partial agonist
5964 SI-2 hydrochloride
Steroid receptor coactivator 3 (SRC-3) inhibitor
3625 SID 26681509
Cathepsin L inhibitor
3440 SID 7969543
Selective steroidogenic factor-1 (SF-1, NR5A1) inhibitor
7432 SIM1
Potent and selective trivalent BET Bromodomain Degrader (PROTAC®)
0756 SIN-1 chloride
Water-soluble NO donor
7969 SIS17
Selective HDAC11 inhibitor
5291 SIS3
Selective Smad3 inhibitor; inhibits TGF-βR1 signaling
7675 SJ 1008030
Selective JAK2 Degrader (PROTAC®)
7542 SJ 1008066
MAGE-A11 inhibitor; disrupts MAGE-A11:PCF11 interaction
7727 SJ 10542
Potent and selective JAK2/3 Degrader (PROTAC®)
7721 SJ 11646
Potent and selective LCK Degrader (PROTAC®)
7720 SJ 6986
Molecular glue; induces degradation of GSPT1/2
7463 SJF 0628
Potent BRAF Degrader (PROTAC®
7464 SJF 0661
Negative control for SJF 0628 (Cat. No. 7463)
7261 SJF 1521
Selective EGFR PROTAC® Degrader
7262 SJF 1528
Potent EGFR PROTAC® Degrader; also degrades HER2
7266 SJF 8240
c-MET PROTAC®; also degrades exon-14-deleted c-MET
7268 SJFα
Potent and selective p38α PROTAC®
7267 SJFδ
Potent and selective p38δ PROTAC®
6187 SK 216
Plasminogen activator inhibitor-1 (PAI-1) inhibitor
7583 SK 575
Potent PARP1 Degrader (PROTAC®)
7588 SK 575-NEG
Negative control for SK 575 (Cat. No. 7583)
1079 (+)-SK&F 10047 hydrochloride
σ1 selective agonist
6398 SKA 121
Positive allosteric modulator of KCa3.1 (IK) channels
3670 SKA 31
KCa3.1 (IK) and KCa2 (SK) channel activator
0922 SKF 38393 hydrobromide
Selective D1-like agonist
1447 SKF 81297 hydrobromide
D1 agonist
1586 SKF 83566 hydrobromide
Potent and selective D1-like antagonist; also inhibits adenylyl cyclase 2
2075 SKF 83822 hydrobromide
Selective D1-like agonist
3866 SKF 86466 hydrochloride
Potent and selective α2 antagonist
1081 SKF 89976A hydrochloride
Potent GAT-1 inhibitor; brain penetrant
1147 SKF 96365 hydrochloride
TRPC channel inhibitor; also inhibits store-operated Ca2+ entry
0379 SKF 97541
Highly potent GABAB agonist; also GABAA-ρ antagonist
2097 SKI II
Selective non-lipid inhibitor of sphingosine kinase
2250 SL 0101-1
Selective ribosomal S6 kinase (RSK) inhibitor
1969 SL 327
Selective inhibitor of MEK1 and MEK2; brain penetrant
3010 SLIGKV-NH2
PAR2 receptor agonist
1468 SLIGRL-NH2
PAR2-activating peptide
6281 SLM 6031434 hydrochloride
Selective sphingosine kinase 2 (Sphk2) inhibitor
8112 SLU-PP-332
Potent pan-ERR agonist
6245 SM 16
Potent TGF-βRI inhibitor; orally bioavailable
5445 SM 324405
Potent TLR7 agonist
0751 SM-21 maleate
Presynaptic cholinergic modulator
5314 SMBA 1
High affinity and selective activator of Bax
4297 SMER 28
Positive regulator of autophagy
4375 SMER 3
Selective inhibitor of E3 ubiquitin ligase
7192 SMIP 004
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
2684 SN 38
DNA topoisomerase I inhibitor; antitumor
2184 SN-6
Selective Na+/Ca2+ exchange inhibitor (reverse mode)
0598 SNAP
A stable analog of endogenous S-nitroso compounds
1561 (S)-SNAP 5114
GABA uptake inhibitor
3347 SNAP 94847 hydrochloride
Potent and selective MCH1 antagonist
1529 SNC 162
Potent, selective non-peptide δ agonist
0764 SNC 80
Highly selective non-peptide δ agonist
7120 SNIPER(ER)-87
Potent and selective ERα Degrader (SNIPER)
0603 SNOG
NO carrier. Breaks down to release NO
4075 SNS 032
Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9
7322 SP 10
Highly potent inhibitor of SARS-CoV Spike (S) protein and ACE2 interaction
5309 SP 100030
NF-κB and AP-1 dual inhibitor
5332 SP 141
High affinity MDM2 inhibitor
1496 SP 600125
Selective JNK inhibitor
7498 SPOP-i-6lc
SPOP E3 ubiquitin ligase inhibitor
5391 SPP 86
Potent RET inhibitor
6597 SPRi 3
Potent sepiapterin reductase (SPR) inhibitor; attenuates proliferation of CD4+ T cells
6055 SPT Imidazopyridine 1
Potent serine palmitoyl transferase inhibitor
1435 SQ 22536
Adenylyl cyclase inhibitor
5868 SR 0987
T cell-specific RORγ (RORγt) agonist
6038 SR 10067
Selective Rev-Erbα/β agonist; anxiolytic
4874 SR 1078
RORα/γ agonist
3411 SR 11237
Pan RXR agonist
2476 SR 11302
AP-1 inhibitor; antitumor agent
2969 SR 12813
Pregnane X receptor agonist
5431 SR 13800
Potent MCT1 inhibitor
4012 SR 140333
Potent NK1 antagonist
0923 SR 141716A
Selective CB1 inverse agonist
2309 SR 142948
Highly potent NTS receptor antagonist
4424 SR 16584
Selective α3β4 nAChR antagonist
6383 SR 16832
Dual site PPARγ inhibitor
2022 SR 202
Selective PPARγ antagonist; antidiabetic and antiobesity agent
4869 SR 2211
Selective RORγ inverse agonist
2190 SR 27897
Potent and selective CCK1 antagonist
5044 SR 3576
Highly potent and selective JNK3 inhibitor
3667 SR 3677 dihydrochloride
Potent, selective Rho-kinase (ROCK) inhibitor
3721 SR 48692
Selective non-peptide NTS1 antagonist
2310 SR 49059
Selective, orally active vasopressin V1A receptor antagonist
1205 SR 57227 hydrochloride
Potent and selective 5-HT3 agonist
3986 SR 58611A hydrochloride
β3 agonist; displays anxiolytic and antidepressant effects
1511 SR 59230A hydrochloride
Potent and selective β3 antagonist
5626 SR 7826
Potent and selective LIMK inhibitor; antitumor
4463 SR 8278
Rev-Erbα antagonist
5855 SR 9009
Rev-Erbα/β agonist
5854 SR 9238
Potent and selective LXR inverse agonist
6138 SR 9243
Selective LXR inverse agonist
1262 SR 95531 hydrobromide
Competitive and selective GABAA antagonist
7558 SRT 1720
Selective SIRT1 activator; induces autophagy and mitochondrial biogenesis
5253 SSM 3 trifluoroacetate
Potent furin inhibitor
3297 SSR 146977 hydrochloride
Potent and selective NK3 antagonist
6195 SSR 149415
Potent and selective vasopressin V1B antagonist
5559 SSR 180711 hydrochloride
Selective α7 nAChR partial agonist
2506 SSR 69071
Potent, orally active human leukocyte elastase inhibitor
7554 SSYA10-001
Potent coronavirus helicase inhibitor; also inhibits human papillomavirus E6
6271 ST 034307
Adenylyl cyclase 1 (AC1) inhibitor; analgesic and active in vivo
6775 ST 045849
O-GlcNAc transferase (OGT) inhibitor
4509 STF 083010
Inhibits IRE1α endonuclease activity
4484 STF 31
NAMPT inhibitor; also GLUT1 inhibitor
8054 STING Degrader N-Me-SP23
Negative control for STING Degrader SP23 (Cat. No. 8053)
8053 STING Degrader SP23
Selective STING Degrader (PROTAC®)
7741 STING agonist C53
Pan-polymorph STING agonist
1551 STO-609 acetate
Selective CaM kinase kinase inhibitor
5570 STOCK2S 26016
Lysine deficient protein kinase (WNK) signaling inhibitor
7341 STX 64
Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II
3304 SU 16f
Potent and selective PDGFRβ inhibitor
3607 SU 3327
Selective JNK inhibitor
3300 SU 5402
Potent FGFR and VEGFR inhibitor
3037 SU 5416
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
6475 SU 6656
Potent ATP-competitive Src family kinase inhibitor; also AMPK inhibitor; cell permeable
2550 SUN-B 8155
Non-peptide calcitonin agonist
5759 SW 033291
High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation
5076 SZL P1-41
Selective Skp2 inhibitor; suppresses E3 ligase activity
0246 Saclofen
Selective GABAB antagonist
5772 Sacubitril calcium
Membrane metallo-endopeptidase (neprilysin) inhibitor prodrug; orally bioavailable
3657 Sal 003
Cell-permeable inhibitor of eIF2α dephosphorylation
0634 Salbutamol hemisulfate
β2-adrenoceptor agonist
4712 Salmeterol xinafoate
Long-acting β2 agonist; bronchodilator
2347 Salubrinal
Selective inhibitor of eIF2α dephosphorylation
5611 Salvinorin B
Activator of κ-opioid DREADD (KORD)
2302 Sanguinarine chloride
Inhibitor of protein phosphatase 2C (PP2C)
7191 Santacruzamate A
Highly potent and selective HDAC2 inhibitor
4418 Saquinavir mesylate
HIV protease inhibitor
7189 Saracatinib
Potent and selective Src tyrosine kinase family inhibitor; anticancer; antiviral; orally bioavailable
3739 Sarpogrelate hydrochloride
Selective 5-HT2A antagonist
6507 Saxagliptin hydrochloride
High affinity DPP-IV inhibitor; active in vivo
2736 Sazetidine A dihydrochloride
α4β2 nAChR ligand; may act as an agonist or a desensitizer
1414 Scopolamine hydrobromide
Non-selective muscarinic antagonist
7449 Se-NADA
Orange fluorescent benzoselenadiazole D-amino acid (FDAA) for imaging bacteria; also photosensitizer
2849 SecinH3
Sec7-specific GEF inhibitor; selective for cytohesin family
1918 Secretin (human)
Gastrointestinal peptide
1919 Secretin (rat)
Gastrointestinal peptide
7760 Selinexor
Selective exportin 1 (XPO1/CRM1) inhibitor
7696 Selpercatinib
Potent and selective RET inhibitor
7555 SenTraGor™
Reagent for staining and detection of lipofuscin in senescent cells
4875 Senexin A
Cdk8 inhibitor
1068 Senktide
Tachykinin NK3 agonist
5553 Sephin 1
Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
0226 D-Serine
Potentiator of NMDA recepors; acts at glycine site
3547 Serotonin hydrochloride
Endogenous 5-HT receptor agonist
2395 Sertraline hydrochloride
5-HT reuptake inhibitor
7544 SiRA 2
Fluorogen for SiRA light-up aptamer. Application: confocal microscopy, SRM (including STED)
3784 Sildenafil citrate
Potent PDE5 inhibitor; orally active
6663 Silodosin
Selective α1A antagonist
1965 Simvastatin
HMG-CoA reductase inhibitor
4044 Sipatrigine
NaV blocker; neuroprotective
5457 SirReal 2
Selective inhibitor of SIRT2
3521 Sirtinol
Selective sirtuin family deacetylase inhibitor
6816 Sitagliptin phosphate
Potent and selective DPP IV inhibitor
3535 Sivelestat sodium salt
Selective leukocyte elastase inhibitor
6424 Sodium Cromoglicate
Promotes ESCs/iPSCs differentiation into pancreatic endocrine islet cells
3850 Sodium butyrate
Histone deacetylase inhibitor
2821 Sodium orthovanadate
Protein tyrosine phosphatase inhibitor
1157 Somatostatin
Influences growth hormone release
1165 Somatostatin 1-28
sst agonist
4185 Sonepiprazole
Selective D4 antagonist
7826 Sonidegib
Potent Smoothened receptor antagonist
6814 Sorafenib
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
0952 Sotalol hydrochloride
β antagonist
5594 Spadin
Potent K2P2.1 (TREK-1) channel blocker
5197 Spautin 1
USP10 and USP13 inhibitor; inhibits autophagy
0958 Spermine tetrahydrochloride
Modulator at polyamine site
6090 Spexin
Potent GAL2/3 agonist; exhibits anxiolytic effects in vivo
1370 Sphingosine-1-phosphate
Endogenous agonist at S1P1-5
2968 Spironolactone
Mineralocorticoid receptor antagonist
6364 Squarunkin A hydrochloride
UNC119 chaperone-cargo interaction inhibitor; disrupts Src activation
3642 Src I1
Dual site Src kinase inhibitor
2798 Stattic
Selective STAT3 inhibitor
1285 Staurosporine
Non-selective protein kinase inhibitor
TB1285-RMU Staurosporine
Staurosporine synthesized to Ancillary Material Grade
7086 StemRegenin 1
Aryl hydrocarbon receptor (AhR) antagonist; promotes HSC expansion and engraftment
1621 Streptozocin
DNA alkylator; antitumor and induces diabetes
1608 Stressin I
CRF1 agonist
1156 Substance P
Sensory neuropeptide; inflammatory mediator
1178 [Sar9,Met(O2)11]-Substance P
Potent and selective NK1 agonist
4935 Sulfasalazine
Inhibitor of NF-κB activation; also inhibits SXC and folate transporter 1
4943 Sulfidefluor 7 AM
H2S fluorescent probe
7302 Sulfo-NHS-LC-Biotin
Amine reactive biotinylation reagent, cell impermeable
0162 S-Sulfo-L-cysteine sodium salt
Group I mGlu agonist
5146 Sulforhodamine 101
Red fluorescent dye; selective astrocyte marker
0894 (RS)-(±)-Sulpiride
Standard selective D2-like antagonist
0895 (S)-(-)-Sulpiride
Standard selective D2-like antagonist
2773 Sumanirole maleate
Selective D2 agonist
3586 Sumatriptan succinate
5-HT1A, 5-HT1B and 5-HT1D agonist
3768 Sunitinib malate
Potent VEGFR, PDGFRβ and KIT inhibitor
1472 Suramin hexasodium salt
Non-selective P2 antagonist
6634 Surfen
Heparin sulfate antagonist
3208 Swainsonine
Inhibitor of α-mannosidase II
5118 SynaptoRedTM C2
Fluorescent dye. Used for: synaptic vesicles staining. Application: fluorescence microscopy

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